Evidence map›Paper›PMID 32054468›Full record

Trial reportBMC complementary medicine and therapies2020

The effect of brushing with Salvadora persica (miswak) sticks on salivary Streptococcus mutans and plaque levels in children: a clinical trial.

Heba J Sabbagh, Khalil S AlGhamdi, Hattan T Mujalled, Sara M Bagher

Registry-linked trialAbstract readRandomized Controlled Trial
In one paragraph

Trial report in BMC complementary medicine and therapies, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04137393 (The Effect of Brushing With Salvadorapersica), which is not on this map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04137393 phase3completednot on this map

The Effect of Brushing With Salvadorapersica (Miswak) Sticks on Salivary Streptococcus Mutants and Plaque Level in Children: A Clinical Trial

TypeinterventionalSponsorHeba sabbaghRan2016 to 2018Enrolled70ConditionsPlaque, DentalArmsbrushing
3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Trial
  2. Article
  3. Review
  4. Article
  5. Article
  6. Review
  7. Article
  8. Review
  9. Article
  10. Evidence-based complementary and alternative medicine : eCAM · 2022
    Review
  11. Article
  12. Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2021
    Review
  13. Antioxidants (Basel, Switzerland) · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Heba J SabbaghPediatric Dentistry Department, King Abdulaziz University, Jeddah, Saudi Arabia. hsabbagh@kau.edu.sa.ORCID http://orcid.org/0000-0002-9788-0379
Khalil S AlGhamdiBani Kabir Primary Health care Centre, Baljurshi Health Sector, Ministry of Health, Albaha, Saudi Arabia.
Hattan T MujalledKing Abdulaziz University, Jeddah, Saudi Arabia.
Sara M BagherPediatric Dentistry Department, King Abdulaziz University, Jeddah, Saudi Arabia.

Funding

King Abdulaziz University G:394-165-1439
6 · The paper itself

Abstract

backgroundThe aim of the randomized double-blinded clinical trial was to evaluate the effect of tooth brushing with Salvadora persica (miswak) sticks on Streptococcus mutans count and the mean plaque score relative to brushing with fluoridated tooth paste (FTP).

methodsOur sample included 94 healthy, high caries-risk, 8 to 9-year-old students recruited from a government school, in Jeddah, Saudi Arabia between February and April 2016. Subjects were randomly grouped into test (provided with miswak sticks) and control groups (provided with FTP and soft brushes). Both groups were introduced to a preparatory period (PPP) of 3 weeks. Plaque score and saliva sampling were conducted prior to the PPP and in follow-up visits by a single, calibrated and blinded dentist.

resultsBoth groups showed a statistically significant decrease in the mean plaque score across the study (P = 0.007 and P = 0.001, respectively). In addition, subjects in the test group with abundant S. sanguinis increased from zero to six after 3 months.

conclusionsSalvadora Persica (miswak) and brushing with FTP significantly reduced plaque scores among school children. In addition, Salvadora persica was found to change the proportions of salivary bacteria in favor of species with less risk of inducing caries.

trial registrationClinicalTrials.gov ID #: NCT04137393.

Indexed as

SalvadoraceaeChildDental Devices, Home CareDental PlaqueDouble-Blind MethodHumansMalePhytotherapySalivaSaudi ArabiaStreptococcus mutansToothbrushingAnd school childrenMiswakPlaque scoreSalivary mutans StreptococciSalvadora Persica

Identifiers

PMID32054468
PMCPMC7076868

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.