ArticleBMC plant biology2020
The TIR-NB-LRR pair DSC1 and WRKY19 contributes to basal immunity of Arabidopsis to the root-knot nematode Meloidogyne incognita.
Article in BMC plant biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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19 citing papers in PubMed, 33 citations in OpenAlex.
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- Advances in molecular interactions between rice and insect herbivores.Crop health · 2024Review
- Insights into the plant response to nematode invasion and modulation of host defense by plant parasitic nematode.Frontiers in microbiology · 2024Review
- AtSWEET1 negatively regulates plant susceptibility to root-knot nematode disease.Frontiers in plant science · 2023Article
- Show me your ID: NLR immune receptors with integrated domains in plants.Essays in biochemistry · 2022Article
- Thirty years of resistance: Zig-zag through the plant immune system.The Plant cell · 2022Review
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- Transcriptomic analysis to reveal the differentially expressed miRNA targets and their miRNAs in response to Ralstonia solanacearum in ginger species.BMC plant biology · 2021Article
- Transcription FactorPlants (Basel, Switzerland) · 2021Article
- A high-quality Brassica napus genome reveals expansion of transposable elements, subgenome evolution and disease resistance.Plant biotechnology journal · 2021Article
- Genome-wide association study for resistance to the Meloidogyne javanica causing root-knot nematode in soybean.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2021Article
- αα-Hub domains and intrinsically disordered proteins: A decisive combo.The Journal of biological chemistryReview
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9 authors at 1 institution in 1 country.
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Abstract
backgroundRoot-knot nematodes transform vascular host cells into permanent feeding structures to withdraw nutrients from the host plant. Ecotypes of Arabidopsis thaliana can display large quantitative variation in susceptibility to the root-knot nematode Meloidogyne incognita, which is thought to be independent of dominant major resistance genes. However, in an earlier genome-wide association study of the interaction between Arabidopsis and M. incognita we identified a quantitative trait locus harboring homologs of dominant resistance genes but with minor effect on susceptibility to the M. incognita population tested.
resultsHere, we report on the characterization of two of these genes encoding the TIR-NB-LRR immune receptor DSC1 (DOMINANT SUPPRESSOR OF Camta 3 NUMBER 1) and the TIR-NB-LRR-WRKY-MAPx protein WRKY19 in nematode-infected Arabidopsis roots. Nematode infection studies and whole transcriptome analyses using the Arabidopsis mutants showed that DSC1 and WRKY19 co-regulate susceptibility of Arabidopsis to M. incognita.
conclusionGiven the head-to-head orientation of DSC1 and WRKY19 in the Arabidopsis genome our data suggests that both genes may function as a TIR-NB-LRR immune receptor pair. Unlike other TIR-NB-LRR pairs involved in dominant disease resistance in plants, DSC1 and WRKY19 most likely regulate basal levels of immunity to root-knot nematodes.
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