ArticleAsian-Australasian journal of animal sciences2020
Hot melt extruded-based nano zinc as an alternative to the pharmacological dose of ZnO in weanling piglets.
Article in Asian-Australasian journal of animal sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed, 26 citations in OpenAlex.
- Biological applications and future perspectives of bioactive compounds as pig feed additives.Animal nutrition (Zhongguo xu mu shou yi xue hui) · 2026Review
- The Aging Gut-Brain Axis: Effects of Dietary Polyphenols and Metal Exposure.Chronic diseases and translational medicine · 2025Review
- The exploitation of nutrient metals by bacteria for survival and infection in the gut.PLoS pathogens · 2025Review
- Mineral interactions in lactating sows: evaluating oxidative stress and productivity during heat stress.Tropical animal health and production · 2025Article
- Lactiplantibacillus argentoratensis AGMB00912 alleviates diarrhea and promotes the growth performance of piglets during the weaning transition.BMC microbiology · 2024Article
- The Mechanism of Zinc Oxide in Alleviating Diarrhea in Piglets after Weaning: A Review from the Perspective of Intestinal Barrier Function.International journal of molecular sciences · 2024Review
- An Updated Review of Emerging Sources of Selenium in Weaned Piglet Nutrition.Animals : an open access journal from MDPI · 2024Review
- Effects of increasing dietary arginine supply during the three first weeks after weaning on pig growth performance, plasma amino acid concentrations, and health status.Translational animal science · 2024Article
- Effects of dietary supplementation of bacteriophage cocktail on health status of weanling pigs in a non-sanitary environment.Journal of animal science and biotechnology · 2023Article
- Metallobiology of Lactobacillaceae in the gut microbiome.Journal of inorganic biochemistry · 2023Review
- Improved Growth Performance, Antioxidant Status, Digestive Enzymes, Nutrient Digestibility and Zinc Bioavailability of Broiler Chickens with Nano-Sized Hot-Melt Extruded Zinc Sulfate.Biological trace element research · 2022Article
- Hot-melt extruded copper sulfate affects the growth performance, meat quality, and copper bioavailability of broiler chickens.Animal bioscience · 2022Article
- Zinc and gut microbiota in health and gastrointestinal disease under the COVID-19 suggestion.BioFactors (Oxford, England) · 2022Review
- Importance of Zinc Nanoparticles for the Intestinal Microbiome of Weaned Piglets.Frontiers in veterinary science · 2022Review
- Supplementation of nano-zinc in lower doses as an alternative to pharmacological doses of ZnO in weanling pigs.Journal of animal science and technology · 2022Article
- Trace metals and animal health: Interplay of the gut microbiota with iron, manganese, zinc, and copper.Animal nutrition (Zhongguo xu mu shou yi xue hui) · 2021Review
- Recent Advances in Understanding the Influence of Zinc, Copper, and Manganese on the Gastrointestinal Environment of Pigs and Poultry.Animals : an open access journal from MDPI · 2021Review
- Effects of Zinc Oxide and Arginine on the Intestinal Microbiota and Immune Status of Weaned Pigs Subjected to High Ambient Temperature.Animals : an open access journal from MDPI · 2020Article
- Sex and Gender Dimensions in Hazard and Risk Assessment of Engineered Nanomaterials.Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnologyReview
Corrections and comments
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Authors and funding
11 authors at 2 institutions in 1 country.
Funding
Abstract
objectiveThis study was conducted to investigate the effects of hot-melt extruded ZnO nano-particles (HME-ZnO) as an alternative for P-ZnO on growth performance, nutrient digestibility, Zn bioavailability, intestinal microbiota, and intestinal morphology of weanling pigs.
methodsA total of 450 piglets (Landrace×Yorkshire×Duroc) were randomly allotted to five treatments based on initial body weight and sex. The experimental diets were fed in a meal form as phase 1 from d 0 to 14 and phase 2 from d 15 to 28. Treatments were the control diet without ZnO supplementation, the diet containing 2,500 ppm Zn as ZnO, and three diets containing 500, 1,000, or 2,500 ppm Zn as HME-ZnO.
resultsThe overall result showed a higher (p<0.01) average daily gain in weanling pigs fed ZnO-supplemented diets in comparison to the control diet. There was a decrease (p<0.01) in fecal score in the ZnO-supplemented diets. Dietary supplementation of ZnO improved (p<0.05) crude protein digestibility. The weanling pigs fed the P-ZnO diet had a lower (p<0.01) Zn digestibility in the feces than HME-ZnO supplemented treatments. Weanling pigs fed diets supplemented with ZnO had greater (p<0.05) Lactobacillus spp. populations and lower Clostridium spp. (p<0.05) and Coliforms (p<0.01) populations in the ileum. Weanling pigs fed diets supplemented with increasing concentrations of HME-ZnO linearly decreased Clostridium spp. (p<0.05) and Coliforms (p<0.01) in the ileum. Lower (p<0.05) Clostridium spp. and Coliforms counts in the colon were observed in pigs fed with ZnO-supplemented diets. Weanling pigs fed diets supplemented with ZnO showed a greater (p<0.01) villus height in the duodenum.
conclusionDietary supplementation of HME-ZnO and P-ZnO showed a potential to improve the digestibility of protein, intestinal Coliform and Clostridium, villus height in duodenum and ileum. Moreover, HME-ZnO showed a higher Zn digestibility compared with P-ZnO.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.