ArticleAnimal bioscience2021
β-Carotene prevents weaning-induced intestinal inflammation by modulating gut microbiota in piglets.
Article in Animal bioscience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
28 citing papers in PubMed, 53 citations in OpenAlex.
- Red palm olein biscuit supplementation modulates gut microbiota in vitamin A deficient rural Malaysian schoolchildren: a randomised controlled trial.Nature communications · 2025Trial
- Healing from the Ocean: Targeting Shared Mechanisms in Autism and Epilepsy Using Algae-Derived Compounds.Marine drugs · 2026Review
- β-Cryptoxanthin Confers Radioprotection against Intestinal Injury via NRF2-Mediated Antioxidant Response and Gut Microbiota Reprogramming.International journal of biological sciences · 2026Article
- Growing Tibetan Pigs Adapt to High-Fiber Diets by Enhancing Fiber Degradation Capacity.Veterinary sciences · 2025Article
- Effects of Cordyceps militaris solid medium on the growth performance, immunity parameters and intestinal health of broilers.Animal bioscience · 2025Article
- Maternal β-carotene supplementation improves offspring growth, development, immunity, and intestinal microbiota in chickens via immune-mediated and microbial-mediated maternal effects.Scientific reports · 2025Article
- Nanoencapsulation enhanced the performance of β-carotene for ameliorating inflammation in patient-derived organoids.Nanomedicine (London, England) · 2025Article
- Design and Bioanalysis of Nanoliposome Loaded with Premium Red Palm Oil for Improved Nutritional Delivery and Stability.Foods (Basel, Switzerland) · 2025Article
- Xylo-oligosaccharides enhance intestinal and thymic immunity by modulating pyroptosis, gut microbiota, and Th17/Treg immune response in lipopolysaccharide-challenged piglets.Journal of animal science · 2025Article
- Maternal β-carotene addition has long-term effects on intestinal health of offspring chicks.Frontiers in microbiology · 2025Article
- The biochemical effects of carotenoids in orange carrots on the colonic proteome in a mouse model of diet-induced obesity.Frontiers in nutrition · 2024Article
- The Use of Fruit and Vegetable by-Products as Enhancers of Health Status of Piglets after Weaning: The Role of Bioactive Compounds from Apple and Carrot Industrial Wastes.Veterinary sciences · 2023Review
- Study of the Anti-Inflammatory Mechanism of β-Carotene Based on Network Pharmacology.Molecules (Basel, Switzerland) · 2023Article
- Comparative Analysis of Rumen Microbiota Composition in Dairy Cows with Simple Indigestion and Healthy Cows.Microorganisms · 2023Article
- Influence of food-derived bioactives on gut microbiota compositions and their metabolites by focusing on neurotransmitters.Food science and biotechnology · 2023Review
- The Effects of Synbiotics on Dextran-Sodium-Sulfate-Induced Acute Colitis: The Impact of Chitosan Oligosaccharides on Endogenous/ExogenousFoods (Basel, Switzerland) · 2023Article
- Carotenoids and Their Health Benefits as Derived via Their Interactions with Gut Microbiota.Advances in nutrition (Bethesda, Md.) · 2023Review
- Early weaning leads to the remodeling of lipid profile in piglet jejunal crypt cells during post-weaning days.Animal nutrition (Zhongguo xu mu shou yi xue hui) · 2022Article
- Immunometabolism in livestock: triggers and physiological role of transcription regulators, nutrients, and microbiota.Animal frontiers : the review magazine of animal agriculture · 2022Article
- Beta-carotene regulates the biological activity of EGF in IEC6 cells by alleviating the inflammatory process.Cell cycle (Georgetown, Tex.) · 2022Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
Abstract
objectiveWeaning is an important stage in the life of young mammals, which is associated with intestinal inflammation, gut microbiota disorders, and even death. β-Carotene displays anti-inflammatory and antioxidant activities, which can prevent the development of inflammatory diseases. However, whether β-carotene can affect intestinal microbiota remains unclear.
methodsTwenty-four piglets were distributed into four groups: the normal suckling group (Con), the weaning group (WG), the weaning+β-carotene (40 mg/kg) group (LCBC), and the weaning+β-carotene (80 mg/kg) group (HCBC). The serum, jejunum, colon, and faeces were collected separately from each group. The effects of β-carotene on the phenotype, overall structure, and composition of gut microbiota were assessed in weaning piglets.
resultsThe results showed that β-carotene improved the growth performance, intestinal morphology and relieved inflammation. Furthermore, β-carotene significantly decreased the species from phyla Bacteroidetes and the genus Prevotella, and Blautia, and increased the species from the phyla Firmicutes and the genera p-75-a5, and Parabacteroides compared to the WG group. Spearman's correlation analysis showed that Prevotella and Blautia were positively correlated, and Parabacteroides and Synergistes were negatively correlated with the levels of interleukin-1β (IL-1β), IL-6, and tumour necrosis factor-α (TNF-α), while p-75-a5 showed negative correlation with IL-6 in serum samples from piglets.
conclusionThese findings indicate that β-carotene could alleviate weaning-induced intestinal inflammation by modulating gut microbiota in piglets. Prevotella may be a potential target of β-carotene in alleviating the weaning-induced intestinal inflammation in piglets.
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