Evidence map›Paper›PMID 32054029›Full record

ReviewInternational journal of molecular sciences2020

Novel Basic Science Insights to Improve the Management of Heart Failure: Review of the Working Group on Cellular and Molecular Biology of the Heart of the Italian Society of Cardiology.

Pietro Ameri, Gabriele Giacomo Schiattarella, Lia Crotti, Margherita Torchio, Edoardo Bertero, Daniele Rodolico, Maurizio Forte, Vittoria Di Mauro, Roberta Paolillo, Cristina Chimenti and 6 more

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Pietro AmeriIRCCS Ospedale Policlinico San Martino-IRCCS Italian Cardiovascular Network & Department of Internal Medicine, University of Genova, 16132 Genova, Italy.
Gabriele Giacomo SchiattarellaDepartment of Internal Medicine (Cardiology), University of Texas Southwestern Medical Center, Dallas, TX 75206, USA.
Lia CrottiIstituto Auxologico Italiano, IRCCS, Department of Cardiovascular, Neural and Metabolic Sciences, San Luca Hospital, 20149 Milan, Italy.
Margherita TorchioIstituto Auxologico Italiano, IRCCS, Istituto Auxologico Italiano, Center for Cardiac Arrhythmias of Genetic Origin, and Laboratory of Cardiovascular Genetics, 20095 Milan, Italy.
Edoardo BerteroComprehensive Heart Failure Center (CHFC), University Clinic Würzburg, 97078 Würzburg, Germany.
Daniele RodolicoAgostino Gemelli Medical School, Catholic University of the Sacred Heart, 00168 Rome, Italy.
Maurizio ForteDepartment of AngioCardioNeurology, IRCCS Neuromed, 86077 Pozzili, Italy.
Vittoria Di MauroNational Research Council (CNR) Institute of Genetics & Biomedical Research, Milan Unit, 20138 Milan, Italy.
Roberta PaolilloDepartment of Advanced Biomedical Sciences, Federico II University, 80131 Naples, Italy.
Cristina ChimentiDepartment of Cardiovascular, Respiratory, Nephrologic, and Geriatric Sciences, Sapienza University of Rome, 00100 Rome, Italy.
Daniele TorellaMolecular and Cellular Cardiology Laboratory, Department of Experimental and Clinical Medicine, Magna Graecia University, 88100 Catanzaro, Italy.
Daniele CatalucciNational Research Council (CNR) Institute of Genetics & Biomedical Research, Milan Unit, 20138 Milan, Italy.
Sebastiano SciarrettaDepartment of AngioCardioNeurology, IRCCS Neuromed, 86077 Pozzili, Italy.
Cristina BassoCardiovascular Pathology, Department of Cardiac, Thoracic, Vascular Sciences and Public Health, University of Padua, 35121 Padua, Italy.
Ciro IndolfiDivision of Cardiology, Department of Medical and Surgical Sciences & Center of Cardiovascular Research, Magna Graecia University, 88100 Catanzaro, Italy.
Cinzia PerrinoDepartment of Advanced Biomedical Sciences, Federico II University, 80131 Naples, Italy.

Funding

H2020 H2020-NMBP-2016 720834Ministero dell'Istruzione, dell'Università e della Ricerca 2015583WMX
6 · The paper itself

Abstract

Despite important advances in diagnosis and treatment, heart failure (HF) remains a syndrome with substantial morbidity and dismal prognosis. Although implementation and optimization of existing technologies and drugs may lead to better management of HF, new or alternative strategies are desirable. In this regard, basic science is expected to give fundamental inputs, by expanding the knowledge of the pathways underlying HF development and progression, identifying approaches that may improve HF detection and prognostic stratification, and finding novel treatments. Here, we discuss recent basic science insights that encompass major areas of translational research in HF and have high potential clinical impact.

Indexed as

AnimalsAutophagyDisease ManagementDrug Delivery SystemsGenetic Predisposition to DiseaseHeart FailureHumansInflammationItalyMicrobiotaMyocytes, CardiacPrognosisSocieties, MedicalTranslational Research, Biomedicalbasicheart failuremechanismsresearchtranslational

Identifiers

PMID32054029
PMCPMC7072832

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.