Evidence map›Paper›PMID 32053105›Full record

ArticleeLife2020

The CHORD protein CHP-1 regulates EGF receptor trafficking and signaling in

Andrea Haag, Michael Walser, Adrian Henggeler, Alex Hajnal

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in eLife, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.3field-weighted citation impact, top 50% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Andrea Haag *Institute of Molecular Life Sciences, University of Zürich, Winterthurerstrasse, Switzerland.
Michael Walser *Institute of Molecular Life Sciences, University of Zürich, Winterthurerstrasse, Switzerland.ORCID 0000-0003-3506-4621
Adrian HenggelerInstitute of Molecular Life Sciences, University of Zürich, Winterthurerstrasse, Switzerland.
Alex HajnalInstitute of Molecular Life Sciences, University of Zürich, Winterthurerstrasse, Switzerland.ORCID 0000-0002-4098-3721
University of Zurich · CH

Funding

Enhancing and expanding the CGC Strain CollectionP40OD010440 · OD · UNIVERSITY OF MINNESOTA · PI Aric L Daul, Ann E. Rougvie · 2012 to 2026
$7.5M
NIH HHS P40 OD010440Swiss National Science Foundation 31003A-166580
6 · The paper itself

Abstract

The intracellular trafficking of growth factor receptors determines the activity of their downstream signaling pathways. Here, we show that the putative HSP-90 co-chaperone CHP-1 acts as a regulator of EGFR trafficking in

Indexed as

Signal TransductionAnimalsCaenorhabditis elegansErbB ReceptorsHSP90 Heat-Shock ProteinsHumansPhosphate-Binding ProteinsProtein TransportCHORDC1 protein, humanEGFR protein, humanErbB ReceptorsHSP90 Heat-Shock ProteinsPhosphate-Binding ProteinsA431C. eleganscell biologychaperoneCHORDdevelopmental biologyEGFRHSP90human

Identifiers

PMID32053105
PMCPMC7062474
OpenAlexW3005956381

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.