ReviewCartilage2021
Particulated Cartilage for Chondral and Osteochondral Repair: A Review.
Review in Cartilage, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
29 citing papers in PubMed, 57 citations in OpenAlex.
- Natural Biomaterials for Osteochondral Repair: From Source to Strategy.Advanced healthcare materials · 2026Review
- Comparison of Bone Marrow Stimulation and Particulated Autologous Cartilage Transplantation for Osteochondral Lesions of the Talus With a 2-Year Follow-up.Orthopaedic journal of sports medicine · 2026Article
- Piezoelectric Biomaterials for Osteochondral Tissue Engineering: Advances, Mechanisms, and Translational Prospects.Journal of functional biomaterials · 2026Review
- Article
- Fibrin Glues: Proteins, Mechanism of Action, Classification, and Application.International journal of molecular sciences · 2025Review
- Cartilage Scaffolds Implanted Without Subchondral Drilling Are Associated With Improved Outcomes and Fewer Complications Compared to Scaffolds Implanted With Subchondral Drilling in the Treatment of Isolated Patellar Cartilage Lesions.Arthroscopy, sports medicine, and rehabilitation · 2025Article
- Microenvironmental response-based treatment of osteoarthritis is a highly effective and durable program: a review.Journal of orthopaedic surgery and research · 2025Review
- A Comprehensive Review of Auto- and Allogeneic Chondrocyte Transplantation in Animals and Humans From 1965 to 2025.Cartilage · 2025Article
- Bioinformatic prediction of key genes involved in pro-chondrogenic effect of fragmentated cartilage transplantation.Scientific reports · 2025Article
- Smart Biomimetic 3D Scaffolds Based on Shape Memory Polyurethane for Soft Tissue Repair.Polymers · 2025Article
- Autologous minced cartilage implantation in osteochondral lesions of the talus-does fibrin make the difference?Archives of orthopaedic and trauma surgery · 2025Article
- Charting a quarter-century of commercial cartilage regeneration products.Journal of orthopaedic translation · 2025Review
- Outcomes of Particulated Juvenile Articular Cartilage and Association With Defect Fill in Patients With Full-Thickness Patellar Chondral Lesions.Orthopaedic journal of sports medicine · 2024Article
- Research progress of procyanidins in repairing cartilage injury after anterior cruciate ligament tear.Heliyon · 2024Review
- The Dual-Responsive Interaction of Particulated Hyaline Cartilage and Plasma Rich in Growth Factors (PRGF) in the Repair of Cartilage Defects: An In Vitro Study.International journal of molecular sciences · 2023Article
- Particulate cartilage and platelet-rich plasma treatment for knee chondral defects in sheep.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2023Article
- Biologic principles of minced cartilage implantation: a narrative review.Archives of orthopaedic and trauma surgery · 2023Review
- Effects of Electrical Stimulation on Articular Cartilage Regeneration with a Focus on Piezoelectric Biomaterials for Articular Cartilage Tissue Repair and Engineering.International journal of molecular sciences · 2023Review
- The autologous chondral platelet-rich plasma matrix implantation. A new therapy in cartilage repair and regeneration: macroscopic and biomechanical study in an experimental sheep model.Frontiers in veterinary science · 2023Article
- Pulsed Electromagnetic Field Therapy and Direct Current Electric Field Modulation Promote the Migration of Fibroblast-like Synoviocytes to Accelerate Cartilage Repair In Vitro.Applied sciences (Basel, Switzerland) · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionInjuries to articular cartilage have a poor spontaneous repair potential and no gold standard treatment exist. Particulated cartilage, both auto- and allograft, is a promising new treatment method that circumvents the high cost of scaffold- and cell-based treatments. MATERIALS AND
methodsA comprehensive database search on particulated cartilage was performed.
resultsFourteen animal studies have found particulated cartilage to be an effective treatment for cartilage injuries. Many studies suggest that juvenile cartilage has increased regenerative potential compared to adult cartilage. Sixteen clinical studies on 4 different treatment methods have been published. (1) CAIS, particulated autologous cartilage in a scaffold, (2) Denovo NT, juvenile human allograft cartilage embedded in fibrin glue, (3) autologous cartilage chips-with and without concomitant bone grafting, and (4) augmented autologous cartilage chips.
conclusionImplantation of allogeneic and autologous particulated cartilage provides a low cost and effective treatment alternative to microfracture and autologous chondrocyte implantation. The methods are promising, but large randomized controlled studies are needed.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.