ArticleJournal of cardiovascular imaging2020
Echocardiographic Assessment of Right Ventriculo-arterial Coupling: Clinical Correlates and Prognostic Impact in Heart Failure Patients Undergoing Cardiac Resynchronization Therapy.
Article in Journal of cardiovascular imaging, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
30 citing papers in PubMed, 1 synthesis or guideline pooled it, 47 citations in OpenAlex.
- The prognostic impact of right ventricular-pulmonary arterial coupling in heart failure: a systematic review and meta-analysis.Heart failure reviews · 2024Pooled it
- Prognostic Value of Non-Invasively Determined Right Ventricular-Arterial Coupling Surrogate Parameters in Patients with Dilated Cardiomyopathy.Journal of clinical medicine · 2026Article
- Advanced Cardiac Imaging for Risk Prediction of Pacing-Induced Cardiomyopathy: A Narrative Literature Review.Journal of clinical medicine · 2026Review
- Right ventricular to pulmonary arterial uncoupling: clinical, functional and morphological insights in patients with hypertrophic cardiomyopathy.The international journal of cardiovascular imaging · 2026Article
- Noninvasive screening for surgery in adults with simple shunting congenital heart disease.BMC cardiovascular disorders · 2026Article
- Prognostic Value of the TAPSE/PASP Ratio in Lung Transplant Candidates With Advanced Interstitial Lung Disease.Pulmonary circulation · 2025Article
- Refining Prognostication and Therapeutic Guidance Through Advances in Right Heart Imaging Approaches.The Canadian journal of cardiology · 2025Review
- Combination Between Biomarkers and Echocardiographic Data for Prediction of Left Ventricular Reverse Remodelling in Cardiac Resynchronization Therapy.Journal of clinical medicine · 2025Article
- Prognostic value of non-invasive right ventricle-pulmonary artery coupling in patients with pulmonary hypertension associated with left heart disease.Journal of cardiothoracic surgery · 2025Article
- Prognostic role of TAPSE to PASP ratio in outpatients with left ventricular systolic dysfunction.ESC heart failure · 2025Article
- The Functional and Imaging Implications of Left Bundle Branch Pacing in Ischemic Cardiomyopathy.Biomolecules · 2025Review
- Comparison of Tricuspid Annular Plane Systolic Excursion to Pulmonary Artery Systolic Pressure Ratio Measured by Transthoracic Echocardiography and Right Heart Catheterization in Pulmonary Arterial Hypertension: Prognostic Implications.Journal of clinical medicine · 2025Article
- Tricuspid annular plane systolic excursion/pulmonary arterial systolic pressure ratio as a predictor of outcome in acute heart failure.La Tunisie medicale · 2025Article
- Right ventricular-pulmonary artery coupling in patients undergoing cardiac resynchronization therapy.The international journal of cardiovascular imaging · 2024Article
- The Effect of Cardiac Resynchronization Therapy on Right Ventricular Function: A Systematic Review and Meta-Analysis.Journal of clinical medicine · 2024Review
- Application of an echocardiographic index to characterize right ventricular-pulmonary arterial coupling in heart failure.ESC heart failure · 2024Review
- Refining cardiac resynchronization therapy: a comprehensive review on the role of advanced multimodality imaging.Frontiers in cardiovascular medicine · 2024Review
- The tricuspid annular plane systolic excursion/PASP ratio's accuracy and validity in assessing the right ventricular function: A narrative review.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2024Review
- Prognostic implication of right ventricular-pulmonary artery coupling in valvular heart disease.Frontiers in cardiovascular medicine · 2024Review
- The Role of Right Ventriculo-Arterial Coupling in Symptoms Presentation of Patients with Hypertrophic Cardiomyopathy.Journal of clinical medicine · 2023Article
Corrections and comments
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Authors and funding
9 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundRight ventriculo-arterial coupling (RV-PA) can be estimated by echocardiography using the ratio between tricuspid annular plane systolic excursion (TAPSE) and pulmonary artery systolic pressure (PASP) and it has prognostic value in the general heart failure (HF) population. We aimed to study the clinical correlates and prognostic value of RV-PA in HF patients undergoing cardiac resynchronization therapy (CRT).
methodsWe retrospectively studied 70 HF patients undergoing CRT implantation.
resultsRV-PA coupling was estimated by TAPSE/PASP ratio using baseline echocardiography. Non-response to CRT was defined as improvement of left ventricular ejection fraction < 5% in a follow-up echo 6-12 months after CRT. Those with lower TAPSE/PASP ratios (worse RV-PA coupling) had higher NT-proBNP concentrations and increased E/e' ratio. TAPSE/PASP ratio and PASP, but not TAPSE, predicted nonresponse to CRT with TAPSE/PASP ratio showing the best discriminative ability with a sensitivity of 76% and specificity of 71%. Among these parameters, PASP independently predicted all-cause mortality.
conclusionsRV-PA coupling estimated by TAPSE/PASP ratio was associated with established prognostic markers in HF. It numerically outperformed PASP and TAPSE in predicting the response to CRT. Our data suggest that this simple and widely available echocardiographic parameter conveys significant pathophysiological and prognostic meaning in HF patients undergoing CRT.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.