Evidence map›Paper›PMID 32052566›Full record

ArticleEarly intervention in psychiatry2021

Longitudinal predictors of stigma in first-episode psychosis: Mediating effects of depression.

Lindsay A Bornheimer, Nicholas Tarrier, Aaron P Brinen, Juliann Li, Meredith Dwyer, Joseph A Himle

Abstract read
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Article in Early intervention in psychiatry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

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3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Lindsay A BornheimerSchool of Social Work, University of Michigan, 1080 S. University Ave., School of Social Work, Ann Arbor, Michigan.ORCID 0000-0002-4684-5696
Nicholas TarrierSchool of Psychological Sciences, University of Manchester, United Kingdom.
Aaron P BrinenCollege of Medicine, Drexel University, Philadelphia, Pennsylvania.
Juliann LiSchool of Social Work, University of Michigan, 1080 S. University Ave., School of Social Work, Ann Arbor, Michigan.
Meredith DwyerSilver School of Social Work, New York University, New York, New York.
Joseph A HimleSchool of Social Work and Department of Psychiatry, University of Michigan, 1080 S. University Ave., School of Social Work, Ann Arbor, Michigan.

Funding

Trials Operation Unit (OPERATIONS CORE)P30MH090590 · NIMH · FEINSTEIN INSTITUTE FOR MEDICAL RESEARCH · PI CORRELL, CHRISTOPH U · 2010 to 2014
$7.9M
NIMH NIH HHS HHSN271200900019CNIMH NIH HHS P30 MH090590
6 · The paper itself

Abstract

aimStigma is commonly experienced among individuals with schizophrenia spectrum disorders and has been shown to be a barrier to help-seeking and behavioural service utilization. Given the established relationships between stigma, barriers to treatment, and poorer psychiatric outcomes including depression and psychotic symptoms, we examined the relationships between symptoms of depression, positive and negative symptoms, and the emergence of stigma longitudinally among a sample of first-episode of psychosis (FEP) participants in the United States.

methodsData were obtained from the Recovery After an Initial Schizophrenia Episode project of National Institute of Mental Health's Early Treatment Program. Participants (n = 404) included adults between ages 15 and 40 with schizophrenia or other psychotic disorders based on the DSM-IV. Data were analysed using structural equation modelling (SEM).

resultsFindings indicated that increased positive and negative symptoms independently related to greater symptoms of depression at baseline. Furthermore, increased positive symptoms and symptoms of depression at baseline independently related to the emergence of greater stigma being experienced over time.

conclusionsConsidering the role that symptoms of depression played as a factor explaining the relationships between positive and negative symptoms and emergence of stigma over time among individuals in FEP, and symptoms of depression is important predictor of stigma and may furthermore present as a viable and less stigmatizing initial treatment target in the early course of a psychotic disorder.

Indexed as

Psychotic DisordersSchizophreniaAdolescentAdultDepressionHumansSocial StigmaYoung Adultdepressionearly interventionfirst episode psychosisnegative symptomspositive symptomsstigmastructural equation modelling

Identifiers

PMID32052566
PMCPMC10731984

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.