Evidence map›Paper›PMID 32052320›Full record

ArticleAnnals of biomedical engineering2020

Fetal Transcatheter Trileaflet Heart Valve Hemodynamics: Implications of Scaling on Valve Mechanics and Turbulence.

Hoda Hatoum, Shelley Gooden, Megan Heitkemper, Kevin M Blum, Jason Zakko, Martin Bocks, Tai Yi, Yen-Lin Wu, Yadong Wang, Christopher K Breuer and 1 more

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Annals of biomedical engineering, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Impact of superhydrophobicity on the fluid dynamics of a bileaflet mechanical heart valve.Journal of the mechanical behavior of biomedical materials · 2020
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 1 country.

Hoda HatoumThe Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology, 387 Technology Circle NW, Atlanta, GA, 30313, USA.
Shelley GoodenThe Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology, 387 Technology Circle NW, Atlanta, GA, 30313, USA.
Megan HeitkemperCenter for Regenerative Medicine, Tissue Engineering Program, The Research Institute at Nationwide Children's Hospital, Columbus, OH, USA.
Kevin M BlumCenter for Regenerative Medicine, Tissue Engineering Program, The Research Institute at Nationwide Children's Hospital, Columbus, OH, USA.
Jason ZakkoCenter for Regenerative Medicine, Tissue Engineering Program, The Research Institute at Nationwide Children's Hospital, Columbus, OH, USA.
Martin BocksCase Western Reserve University School of Medicine, UH Rainbow Babies & Children's Hospital, Cleveland, OH, USA.
Tai YiCenter for Regenerative Medicine, Tissue Engineering Program, The Research Institute at Nationwide Children's Hospital, Columbus, OH, USA.
Yen-Lin WuMeinig School of Biomedical Engineering, Cornell University, Ithaca, NY, USA.
Yadong WangMeinig School of Biomedical Engineering, Cornell University, Ithaca, NY, USA.
Christopher K BreuerCenter for Regenerative Medicine, Tissue Engineering Program, The Research Institute at Nationwide Children's Hospital, Columbus, OH, USA.
Lakshmi Prasad DasiThe Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology, 387 Technology Circle NW, Atlanta, GA, 30313, USA. lakshmi.dasi@gatech.edu.
Nationwide Children's Hospital · USCornell University · USThe Wallace H. Coulter Department of Biomedical Engineering · USCase Western Reserve University · USGeorgia Institute of Technology · US

Funding

Superhydrophobic Heart Valve ProsthesisR01HL135505 · NHLBI · OHIO STATE UNIVERSITY · PI DASI, LAKSHMI PRASAD, KOTA, ARUN KUMAR · 2017 to 2020
$2.9M
Hyaluronan enhanced polymeric heart valve prosthesisR01HL119824 · NHLBI · OHIO STATE UNIVERSITY · PI DASI, LAKSHMI PRASAD · 2013 to 2017
$1.7M
Superomniphobic flow controlled prosthetic heart valveR21HL139208 · NHLBI · OHIO STATE UNIVERSITY · PI DASI, LAKSHMI PRASAD, KOTA, ARUN KUMAR · 2018 to 2019
$408k
American Heart Association 19POST34380804NHLBI NIH HHS R01 HL119824NHLBI NIH HHS R01 HL135505NHLBI NIH HHS R21 HL139208NIH HHS R01HL119824
6 · The paper itself

Abstract

The scarcity of data available on the best approach for pulmonary fetal valve replacement or implantation necessitate an investigation on whether practices using adult transcatheter valves could be translated to fetal applications. The objective of this study is to evaluate the hemodynamic characteristics and the turbulent properties of a fetal sized trileaflet transcatheter pulmonary valve in comparison with an adult balloon-expandable valve in order to assess the possibility of designing valves for fetal applications using dynamic similarity. A 6 mm fetal trileaflet valve and a 26 mm SAPIEN 3 valve were assessed in a pulse duplicator. Particle image velocimetry was performed. Pressure gradient (ΔP), effective orifice area (EOA), regurgitant fractions (RF), pinwheeling indices (PI) and turbulent stresses were evaluated. ΔP was 8.56 ± 0.139 and 7.76 ± 0.083 mmHg with fetal valve and SAPIEN respectively (p < 0.0001); EOA was 0.10 ± 0.0007 and 2.1 ± 0.025 cm

Indexed as

FetusHeart Valve Prosthesis ImplantationAdultAlloysAluminumHeart Valve ProsthesisHeart ValvesHemodynamicsHumansStress, MechanicalZincAlloysAluminumZincBalloon-expandable valveBlood damageDynamic similarityFetal valveHemodynamicsTranscatheter aortic valve replacement

Identifiers

PMID32052320
PMCPMC7286783
OpenAlexW3006006257

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.