ArticleAnnals of surgical oncology2020
Conditional Survival After Resection for Pancreatic Cancer: A Population-Based Study and Prediction Model.
Article in Annals of surgical oncology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.
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43 citing papers in PubMed.
- Dendritic Cell-Based Immunotherapy in Patients With Resected Pancreatic Cancer.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2024Trial
- Lymph node-targeted, mKRAS-specific amphiphile vaccine in pancreatic cancer: the randomized phase 2 AMPLIFY-7P trial.Nature medicine · 2026Article
- Long-term conditional relative survival trends in extrahepatic bile duct cancer: insights from a population-based retrospective cohort study in a high-incidence Asian Country, 1999-2021.International journal of surgery (London, England) · 2026Article
- Article
- Enhanced temporal encoding-decoding for survival analysis of multimodal clinical data in smart healthcare.Visual computing for industry, biomedicine, and art · 2025Article
- Construction of conditional survival nomograms for metastatic early onset colon cancer patients.Journal of gastrointestinal oncology · 2025Article
- Review
- Real-time survival assessment in breast cancer with liver metastasis.Discover oncology · 2025Article
- Conditional survival analysis and real-time prognosis prediction for prostate cancer patients.Scientific reports · 2025Article
- Individualized estimation of conditional survival for patients with spinal chordoma.Translational cancer research · 2025Article
- Verticillin A-Loaded Surgical Buttresses Prevent Local Pancreatic Cancer Recurrence in a Murine Model.Molecular pharmaceutics · 2025Article
- Assessment of intermediate-term mortality following pancreatectomy for cancer.Journal of the National Cancer Institute · 2025Article
- The Spanish Familial Pancreatic Cancer Registry (PANGENFAM): a decade follow-up of individuals at high-risk for pancreatic cancer.Familial cancer · 2024Article
- Article
- Conditional survival and the prognostic value of serum carcinoembryonic antigen level in oldest old with colorectal cancer.BMC gastroenterology · 2024Article
- Individualized prediction of conditional survival for colorectal signet-ring cell carcinoma patients.Annals of medicine and surgery (2012) · 2024Article
- The high FKBP1A expression in WBCs as a potential screening biomarker for pancreatic cancer.Scientific reports · 2024Article
- Conditional Relative Survival of Exocrine Pancreatic Cancer: A Population-Based Study.Annals of surgical oncology · 2024Article
- Dynamic assessment of long-term survival in survivors with stage III non-small cell lung cancer: a novel conditional survival model with a web-based calculator.Frontiers in medicine · 2024Article
- Conditional survival of elderly primary central nervous system lymphoma.Journal of cancer research and clinical oncology · 2023Article
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19 authors.
Funding
Abstract
backgroundConditional survival is the survival probability after already surviving a predefined time period. This may be informative during follow-up, especially when adjusted for tumor characteristics. Such prediction models for patients with resected pancreatic cancer are lacking and therefore conditional survival was assessed and a nomogram predicting 5-year survival at a predefined period after resection of pancreatic cancer was developed.
methodsThis population-based study included patients with resected pancreatic ductal adenocarcinoma from the Netherlands Cancer Registry (2005-2016). Conditional survival was calculated as the median, and the probability of surviving up to 8 years in patients who already survived 0-5 years after resection was calculated using the Kaplan-Meier method. A prediction model was constructed.
resultsOverall, 3082 patients were included, with a median age of 67 years. Median overall survival was 18 months (95% confidence interval 17-18 months), with a 5-year survival of 15%. The 1-year conditional survival (i.e. probability of surviving the next year) increased from 55 to 74 to 86% at 1, 3, and 5 years after surgery, respectively, while the median overall survival increased from 15 to 40 to 64 months at 1, 3, and 5 years after surgery, respectively. The prediction model demonstrated that the probability of achieving 5-year survival at 1 year after surgery varied from 1 to 58% depending on patient and tumor characteristics.
conclusionsThis population-based study showed that 1-year conditional survival was 55% 1 year after resection and 74% 3 years after resection in patients with pancreatic cancer. The prediction model is available via www.pancreascalculator.com to inform patients and caregivers.
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