Evidence map›Paper›PMID 32052200›Full record

ArticleMikrochimica acta2020

The benefits of carbon black, gold and magnetic nanomaterials for point-of-harvest electrochemical quantification of domoic acid.

Joost L D Nelis, Davide Migliorelli, Safiye Jafari, Silvia Generelli, Javier Lou-Franco, J Pablo Salvador, M Pilar Marco, Cuong Cao, Christopher T Elliott, Katrina Campbell

Open access · hybridAbstract read
In one paragraph

Article in Mikrochimica acta, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.4field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 31 citations in OpenAlex.

  1. Review
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  6. Smartphone-based optical assays in the food safety field.Trends in analytical chemistry : TRAC · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 3 countries.

Joost L D NelisInstitute for Global Food Security, School of Biological Sciences, Queen's University, 19 Chlorine Gardens, Belfast, BT9 5DL, UK. J.Nelis@qub.ac.uk.ORCID http://orcid.org/0000-0002-6675-2606
Davide MigliorelliCSEM SA, Bahnhofstrasse 1, 7302, Landquart, Switzerland.
Safiye JafariCSEM SA, Bahnhofstrasse 1, 7302, Landquart, Switzerland.
Silvia GenerelliCSEM SA, Bahnhofstrasse 1, 7302, Landquart, Switzerland.
Javier Lou-FrancoInstitute for Global Food Security, School of Biological Sciences, Queen's University, 19 Chlorine Gardens, Belfast, BT9 5DL, UK.
J Pablo SalvadorNanobiotechnology for Diagnostics (Nb4D), Institute for Advanced Chemistry of Catalonia (IQAC) of the Spanish Council for Scientific Research (CSIC), Jordi Girona 18-26, 08034, Barcelona, Spain.
M Pilar MarcoNanobiotechnology for Diagnostics (Nb4D), Institute for Advanced Chemistry of Catalonia (IQAC) of the Spanish Council for Scientific Research (CSIC), Jordi Girona 18-26, 08034, Barcelona, Spain.
Cuong CaoInstitute for Global Food Security, School of Biological Sciences, Queen's University, 19 Chlorine Gardens, Belfast, BT9 5DL, UK.
Christopher T ElliottInstitute for Global Food Security, School of Biological Sciences, Queen's University, 19 Chlorine Gardens, Belfast, BT9 5DL, UK.
Katrina CampbellInstitute for Global Food Security, School of Biological Sciences, Queen's University, 19 Chlorine Gardens, Belfast, BT9 5DL, UK.
Queen's University Belfast · GBSwiss Center for Electronics and Microtechnology (Switzerland) · CHBiomedical Research Networking Center in Bioengineering, Biomaterials and Nanomedicine · ES

Funding

H2020 Marie Skłodowska-Curie Actions 720325
6 · The paper itself

Abstract

Gold nanostars (GNST), gold nanospheres (GNP) and carbon black (CB) are chosen as alternative nanomaterials to modify carbon screen-printed electrodes (c-SPEs). The resulting three kinds of modified c-SPEs (GNP-SPE, CB-SPE and GNSP-SPE) were electrochemically and microscopically characterized and compared with standardized c-SPEs after pretreatment with phosphate buffer by pre-anodization (pre-SPE). The results show outstanding electrochemical performance of the carbon black-modified SPEs which show low transient current, low capacitance and good porosity. A competitive chronoamperometric immunoassay for the shellfish toxin domoic acid (DA) is described. The performances of the CB-SPE, GNP-SPE and pre-SPE were compared. Hapten-functionalized magnetic beads were used to avoid individual c-SPE functionalization with antibody while enhancing the signal by creating optimum surface proximity for electron transfer reactions. This comparison shows that the CB-SPE biosensor operated best at a potential near - 50 mV (vs. Ag/AgCl) and enables DA to be determined with a detection limit that is tenfold lower compared to pre-SPE (4 vs. 0.4 ng mL

Indexed as

Biosensing TechniquesCarbonElectrochemical TechniquesGoldKainic AcidNanostructuresCarbondomoic acidGoldKainic AcidAmperometryBiosensorFood analysesMarine toxinMaterial characterizationPoint of carePoint of siteShellfishToxin

Identifiers

PMID32052200
PMCPMC7015955
OpenAlexW3006134975

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.