Evidence map›Paper›PMID 32052199›Full record

ReviewCurrent cardiology reports2020

Sex Differences in Coronary Artery Calcium and Long-term CV Mortality.

Allison Bigeh, Chandana Shekar, Martha Gulati

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current cardiology reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
1.9field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it, 31 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Observational
  6. Review
  7. Article
  8. Review
  9. Review
  10. Long-term outcomes of lung cancer screening in males and females.Lung cancer (Amsterdam, Netherlands) · 2023
    Article
  11. Review
  12. Article
  13. Gender Medicine in Clinical Radiology Practice.Journal of personalized medicine · 2023
    Review
  14. Sex Differences in Subclinical Atherosclerosis and Systemic Immune Activation/Inflammation Among People With Human Immunodeficiency Virus in the United States.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2023 · on this map
    Article
  15. Sex Differences in Coronary Atherosclerosis.Current atherosclerosis reports · 2022
    Review
  16. Review
  17. Review
  18. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Allison BigehDepartment of Medicine, Division of Cardiology at the University of Arizona, Phoenix, AZ, USA.
Chandana ShekarDepartment of Medicine, Division of Cardiology at the University of Arizona, Phoenix, AZ, USA.
Martha GulatiDepartment of Medicine, Division of Cardiology at the University of Arizona, Phoenix, AZ, USA. marthagulati@email.arizona.edu.
University of Arizona · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purpose of reviewTo summarize differences in plaque depositions, coronary artery calcium (CAC) scoring, and the role of CAC in predicting atherosclerotic cardiovascular disease (ASCVD) mortality in men and women. RECENT

findingsWomen have coronary plaque that is more lipid-rich, dense, and less calcified than their male counterparts. CAC scoring has emerged as a useful tool to quantify ASCVD burden. However, recent evidence favors the use of sex-adjusted CAC cutoffs for women to account for the relatively lower overall CAC burden and therefore risk stratify women appropriately. Several studies have identified CAC distribution patterns in women associated with increased CV mortality, particularly the number of lesions involved, CAC volume, and size. Multiple studies have shown that the pathophysiology and associated risks of ASCVD are different in women when compared with men. CAC scoring is a tool that is widely being used for ASCVD risk stratification. Recent studies have shown that although men have higher CAC burdens, women are more likely to develop plaque erosions with non-calcified plaque that carries a greater risk for cardiovascular events. Providers should be aware of sex-specific CAC patterns carrying increased mortality risk for women, particularly increasing lesion size and number. Given the differences in plaque composition and distribution, revised sex-adjusted CAC scoring is suggested to better risk stratify patients, especially those deemed intermediate risk, and decrease CV mortality.

Indexed as

Coronary Artery DiseaseVascular CalcificationCalciumCarotid Artery DiseasesCoronary VesselsFemaleHumansMalePlaque, AtheroscleroticPrognosisRisk AssessmentRisk FactorsSex FactorsCalciumAtherosclerosisCardiovascular diseaseCoronary artery calciumPreventionSex differencesWomen

Identifiers

PMID32052199
OpenAlexW3005926959

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.