ReviewAdvances in radiation oncology
Technical Principles of Dual-Energy Cone Beam Computed Tomography and Clinical Applications for Radiation Therapy.
Review in Advances in radiation oncology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- A systematic review of volumetric image guidance in proton therapy.Physical and engineering sciences in medicine · 2023Pooled it
- Pooled it
- A Dual-Energy CBCT With Reduced Scatter and Cone Beam Artifacts Using an X-Ray Source Array and Interlaced Spectral Filters.IEEE transactions on bio-medical engineering · 2026Article
- Impact of dose allocation between high- and low-kV scans on virtual monoenergetic image quality in developmental dual-energy cone-beam CT for image-guided radiotherapy.Journal of applied clinical medical physics · 2026Article
- Refining imaging parameters for dual-energy cone-beam computed tomography in image-guided radiation therapy.Journal of applied clinical medical physics · 2026Article
- Experimental evaluation of an intraoperative-imaging based workflow for electron beam radiotherapy of pancreatic cancer using in situ dosimetry.Journal of applied clinical medical physics · 2026Article
- Optimization-based image reconstruction regularized with inter-spectral structural similarity for limited-angle dual-energy cone-beam CT.Physics in medicine and biology · 2025Article
- Embracing the Future of Clinical Trials in Radiation Therapy: An NRG Oncology CIRO Technology Retreat Whitepaper on Pioneering Technologies and AI-Driven Solutions.International journal of radiation oncology, biology, physics · 2025Review
- Fast, automated optimization of virtual monoenergetic images with the dual-energy image synthesizer for cone-beam CT.Journal of applied clinical medical physics · 2025Article
- Utility of photon-counting detectors for MV-kV dual-energy computed tomography imaging.Journal of medical imaging (Bellingham, Wash.) · 2024Article
- Low-cost dual-energy CBCT by spectral filtration of a dual focal spot X-ray source.Scientific reports · 2024Article
- Technical note: TIGRE-DE for the creation of virtual monoenergetic images from dual-energy cone-beam CT.Medical physics · 2024Article
- Dual-energy computed tomography imaging with megavoltage and kilovoltage X-ray spectra.Journal of medical imaging (Bellingham, Wash.) · 2024Article
- Feasibility of dual-energy CBCT material decomposition in the human torso with 2D anti-scatter grids and grid-based scatter sampling.Medical physics · 2024Article
- Review
- Image guidance for FLASH radiotherapy.Medical physics · 2022Article
- Article
- Characterization and comparison of imaging contrast enhancement with PEG-functionalized gold nanoparticles in kV cone beam computed tomography and computed tomography imaging.Biomedical physics & engineering express · 2020Article
- 3D printed CT-based abdominal structure mannequin for enabling research.3D printing in medicine · 2020Article
- The Top 10 Downloads of 2020 in ASTRO'sAdvances in radiation oncologyArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeMedical imaging is an indispensable tool in radiotherapy for dose planning, image guidance and treatment monitoring. Cone beam CT (CBCT) is a low dose imaging technique with high spatial resolution capability as a direct by-product of using flat-panel detectors. However, certain issues such as x-ray scatter, beam hardening and other artifacts limit its utility to the verification of patient positioning using image-guided radiotherapy. METHODS AND MATERIALS: Dual-energy (DE)-CBCT has recently demonstrated promise as an improved tool for tumor visualization in benchtop applications. It has the potential to improve soft-tissue contrast and reduce artifacts caused by beam hardening and metal. In this review, the practical aspects of developing a DE-CBCT based clinical and technical workflow are presented based on existing DE-CBCT literature and concepts adapted from the well-established library of work in DE-CT. Furthermore, the potential applications of DE-CBCT on its future role in radiotherapy are discussed. RESULTS AND
conclusionsBased on current literature and an investigation of future applications, there is a clear potential for DE-CBCT technologies to be incorporated into radiotherapy. The applications of DE-CBCT include (but are not limited to): adaptive radiotherapy, brachytherapy, proton therapy, radiomics and theranostics.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.