Evidence map›Paper›PMID 32051880›Full record

ArticleHeliyon2020

Comparison of different dietary sources of n-3 polyunsaturated fatty acids on immune response in broiler chickens.

H Al-Khalaifah, A Al-Nasser, D I Givens, C Rymer, P Yaqoob

Open access · goldAbstract read
In one paragraph

Article in Heliyon, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
4.7field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 38 citations in OpenAlex.

  1. Article
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  9. Article
  10. Effects From Dietary Addition ofFrontiers in veterinary science · 2022
    Article
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  12. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

H Al-KhalaifahEnvironment and Life Sciences Research Center, Kuwait Institute for Scientific Research, Kuwait.
A Al-NasserEnvironment and Life Sciences Research Center, Kuwait Institute for Scientific Research, Kuwait.
D I GivensInstitute for Food, Nutrition, and Health, University of Reading, United Kingdom.
C RymerInstitute for Food, Nutrition, and Health, University of Reading, United Kingdom.
P YaqoobDepartment of Food and Nutritional Sciences, Whiteknights House 3-07, University of Reading, United Kingdom.
University of Reading · GBKuwait Institute for Scientific Research · KW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The study aims to research the effects of varied dietary sources of n-3 polyunsaturated fatty acids (PUFA) on the immune response in broiler chickens with stress on natural killer (NK) cell activity. Diets supplemented with one of the four sources of n-3 PUFA: linseed oil-, echium oil-, fish oil (FO) or algal biomass-enriched diets at levels of 18, 18, 50 and 15 g/kg fresh weight, were provided for one-d-old male Ross 308 broilers, totaling 340 in number, until they were slaughtered. The analyses included total lipid profile using gas chromatography (GC) for plasma, spleen, thymus, and blood. Additionally, NK cell activity and cell proliferation were investigated for thymocytes and splenocytes. The results indicated that the source of n-3 PUFA had a strong influence on fatty acid composition across all tissues. NK activity was highest in splenocytes and PBMCs from broilers fed linseed oil, followed by those fed algal biomass or echium oil, and lowest for those from broilers fed FO. The proliferative response of lymphocytes from algal biomass-fed chickens tended to be the highest, followed by those fed linseed oil in most cases. Lymphocytes from chickens fed fish oil showed the lowest proliferative response. These results could mean that a docosahexaenoic acid (DHA)-rich algal product might enrich chicken meat with n-3 PUFA without significant damaging effects on chicken immunity.

Indexed as

Agricultural technologyAnimal behaviorAnimal breedingAnimal scienceCell proliferationDocosahexaenoic acid (DHA)Immunologyn-3 fatty acidsNK cell activity

Identifiers

PMID32051880
PMCPMC7002886
OpenAlexW3003714804

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.