Evidence map›Paper›PMID 32051868›Full record

ArticleHeliyon2020

Protective role of diosgenin against hyperglycaemia-mediated cerebral ischemic brain injury in zebrafish model of type II diabetes mellitus.

Oyesolape B Oyelaja-Akinsipo, Enock O Dare, Deepshikha P Katare

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Heliyon, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.0field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 25 citations in OpenAlex.

  1. Starch Biopolymer Functionalized withCurrent drug delivery · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Oyesolape B Oyelaja-AkinsipoDepartment of Chemical Sciences, College of Science and Information Technology, Tai Solarin University of Education, Ijagun, Ogun State, PMB 2118, Nigeria.
Enock O DareDepartment of Chemistry, College of Physical Sciences, Federal University of Agriculture, Alabata, Abeokuta Ogun State, 110282, Nigeria.
Deepshikha P KatareCentre for Medical Biotechnology, Amity Institute of Biotechnology, Amity University, Noida, Uttar Pradesh, 201303, India.
Federal University of Agriculture · NGAmity University · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Impairment in glucose regulation is an indicatory effect capable of mediating multiple dysfunction such as cerebrovascular disorder with ischemia and brain damage inclusive. This study aims at investigating the glucose-lowering and neuroprotective capability of Diosgenin (DG) towards hyperglycemia-induced cerebral injury in a developed type 2 diabetes mellitus (T2DM) Zebrafish (ZF) model. T2DM was developed in ZF with 20 mg/kg body weight (

Indexed as

Behavioral neuroscienceBrain injuryChemistryDark/light testDiosgeninDrug deliveryDrug developmentHyperglycaemiaIschemiaNeuroprotectionNeuroscienceNeurotoxicologyNovel tank testPharmaceutical sciencePharmacologyStreptozotocinType 2 diabetes mellitusZebrafish

Identifiers

PMID32051868
PMCPMC7002854
OpenAlexW3003417607

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.