ArticleBioMed research international2020
Clinical Characteristics of 162 Patients with Drug-Induced Liver and/or Kidney Injury.
Article in BioMed research international, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
3 citing papers in PubMed.
- Renal injury in NSAIDs: a real-world analysis based on the FAERS database.International urology and nephrology · 2025Article
- Clinical Characteristics and Outcomes of Patients With Antithyroid Drug-Related Liver Injury.Journal of the Endocrine Society · 2023Review
- Review
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Authors and funding
2 authors.
Funding
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Abstract
contextDrug-induced liver and kidney injuries are the most common adverse drug reactions in the clinic, and they have similar pathogeneses.
aimsTo analyze the clinical characteristics of patients with drug-induced liver and/or kidney injury. SETTINGS AND
designThis was a retrospective study. METHODS AND MATERIALS: We analyzed data from 162 patients with drug-induced liver and/or kidney injury from 2008 to 2018 at the Chinese Rocket Force Characteristic Medical Center. Univariate and multivariate logistic analyses were performed on the drugs used, sex, age, weight, complications, and laboratory test results. Statistical analysis was performed using SPSS 25.0 statistical software.
results(1) The most common drugs causing organ injury in this study were antineoplastic drugs, antibiotics, traditional Chinese medicine, lipid-lowering drugs, and nonsteroidal anti-inflammatory drugs. (2) Among 22 patients with drug-induced liver and kidney injuries, 68.18% had a hepatocellular pattern, 13.64% had a mixed pattern, and 18.18% had a cholestatic pattern. Among the three groups, the
conclusions(1) The serum creatinine level was higher in liver injury patients with the cholestatic pattern than in those with the hepatocellular or mixed pattern. (2) There was a significant difference in urinary protein between the isolated kidney and the liver and kidney injury groups. (3) Among patients with drug-induced organ injury, those with a higher neutrophils percentage had a lower risk of liver injury.
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