Evidence map›Paper›PMID 32051824›Full record

ArticleBioMed research international2020

Chinese Herbal Formulas Miao-Yi-Ai-Tang Inhibits the Proliferation and Migration of Lung Cancer Cells through Targeting

Bo Li, Wei Zhang, Tao Tan, Wei Liu, Xian Luo, Jun Zhang, Yi Yang, Ruogu Li, Zhengxing Ge

Open access · hybridAbstract read
In one paragraph

Article in BioMed research international, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.8field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Inhibition of vitamin D analog eldecalcitol on hepatomaOpen medicine (Warsaw, Poland) · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Bo LiDepartment of Respiratory Medicine, The First Affiliated Hospital of Guangzhou University of Traditional Chinese Medicine, No. 16, Baiyun Airport Road, Baiyun District, Guangzhou, Guangdong Province, China.ORCID https://orcid.org/0000-0003-0663-8788
Wei ZhangDepartment of Respiratory Medicine, The First Affiliated Hospital of Guangzhou University of Traditional Chinese Medicine, No. 16, Baiyun Airport Road, Baiyun District, Guangzhou, Guangdong Province, China.ORCID https://orcid.org/0000-0003-4423-1030
Tao TanDepartment of Respiratory Medicine, The Second Affiliated Hospital of Guizhou University of Traditional Chinese Medicine, No. 32, Feishan Road, Yunyan District, Guiyang 550001, Guizhou Province, China.ORCID https://orcid.org/0000-0002-0616-3121
Wei LiuDepartment of Respiratory Medicine, The Second Affiliated Hospital of Guizhou University of Traditional Chinese Medicine, No. 32, Feishan Road, Yunyan District, Guiyang 550001, Guizhou Province, China.ORCID https://orcid.org/0000-0003-2594-000X
Xian LuoDepartment of Respiratory Medicine, The Second Affiliated Hospital of Guizhou University of Traditional Chinese Medicine, No. 32, Feishan Road, Yunyan District, Guiyang 550001, Guizhou Province, China.ORCID https://orcid.org/0000-0002-0455-273X
Jun ZhangDepartment of Respiratory Medicine, The Second Affiliated Hospital of Guizhou University of Traditional Chinese Medicine, No. 32, Feishan Road, Yunyan District, Guiyang 550001, Guizhou Province, China.ORCID https://orcid.org/0000-0002-0768-181X
Yi YangDepartment of Respiratory Medicine, The Second Affiliated Hospital of Guizhou University of Traditional Chinese Medicine, No. 32, Feishan Road, Yunyan District, Guiyang 550001, Guizhou Province, China.ORCID https://orcid.org/0000-0002-1337-6870
Ruogu LiDepartment of Respiratory Medicine, The Second Affiliated Hospital of Guizhou University of Traditional Chinese Medicine, No. 32, Feishan Road, Yunyan District, Guiyang 550001, Guizhou Province, China.ORCID https://orcid.org/0000-0002-2004-4268
Zhengxing GeDepartment of Respiratory Medicine, The Second Affiliated Hospital of Guizhou University of Traditional Chinese Medicine, No. 32, Feishan Road, Yunyan District, Guiyang 550001, Guizhou Province, China.ORCID https://orcid.org/0000-0002-9968-6879
Affiliated Hospital of Guizhou Medical University · CNFirst Affiliated Hospital of Guangzhou University of Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveLung cancer is one of the major causes of cancer deaths worldwide, and the five-year survival still remains low despite the improvement of screening, prevention, and treatment methods. Chinese herbal medicines have been widely used for tumor prevention and treatment. Miao-Yi-Ai-Tang (Miao) is a novel herbal formulation and shows a potential anticancer effect.

resultsWe found that Miao could inhibit invasion, migration, and proliferation and promote apoptosis of human lung cancer cells. Meanwhile, Miao and DDP presented synergy regulating the proliferation and apoptosis of lung cancer cells. The percentage of lung cancer cells in S and G2 stages was increased markedly by Miao. Besides, the expression of c-myc, AXIN, and

conclusionsChinese herbal formulas Miao could suppress lung cancer through targeting the

Indexed as

ApoptosisAxin Proteinbeta CateninCell CycleCell Line, TumorCell MovementCell ProliferationCephalotaxusDrugs, Chinese HerbalGene Expression Regulation, NeoplasticHedyotisHumansLung NeoplasmsSolanumWound HealingAxin Proteinbeta CateninCTNNB1 protein, humanDrugs, Chinese Herbal

Identifiers

PMID32051824
PMCPMC6995313
OpenAlexW3002486770

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.