Evidence map›Paper›PMID 32051811›Full record

ArticleCurrent clinical microbiology reports2019

Extracellular Vesicles in Epstein-Barr Virus Pathogenesis.

Allaura S Cone, Sara B York, David G Meckes

Open access · greenAbstract read
In one paragraph

Article in Current clinical microbiology reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 25 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
  5. The Role of Extracellular Vesicles in Epstein-Barr Virus Immunology and Pathogenesis for Possible Diagnostic and Therapeutic Direction.The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2026
    Review
  6. Review
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Review
  14. Article
  15. Review
  16. Review
  17. Review
  18. Role of Extracellular Vesicles in Influenza Virus Infection.Frontiers in cellular and infection microbiology · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Allaura S ConeDepartment of Biomedical Sciences, Florida State University College of Medicine, Tallahassee, FL 32306, USA.
Sara B YorkDepartment of Biomedical Sciences, Florida State University College of Medicine, Tallahassee, FL 32306, USA.
David G MeckesDepartment of Biomedical Sciences, Florida State University College of Medicine, Tallahassee, FL 32306, USA.
Florida State University · US

Funding

Modulation of Host Cell Exosome Content and Function by EBV LMP1R01CA204621 · NCI · FLORIDA STATE UNIVERSITY · PI MECKES, DAVID G · 2016 to 2020
$2.2M
NCI NIH HHS R01 CA204621
6 · The paper itself

Abstract

purpose of reviewEpstein-Barr virus (EBV) is a known determinant for numerous malignancies and may contribute to autoimmune diseases. The underlining mechanisms behind EBV pathologies is not completely understood. Recently, extracellular vesicles (EVs) released from infected cells have been found to produce profound effects on cellular microenvironments. Therefore, in this review we sought to critically evaluate the roles of EVs in EBV pathogenesis and assess their potential therapeutic and diagnostic utility. RECENT

findingsEBV-altered EVs are capable of activating signaling cascades and phenotypic changes in recipient cells through the transfer of viral proteins and RNAs. Moreover, several EV-associated microRNAs have encouraging prognostic or diagnostic potential in EBV-associated cancers. SUMMARY: Current evidence suggests that EBV-modified EVs affect viral pathogenesis and cancer progression. However, further research is needed to investigate the direct role of both viral and host products on recipient cells and the mechanisms driving viral protein and RNA EV packaging and content modification.

Indexed as

autoimmunecancerdiagnosticEpstein-Barr virusexosomesextracellular vesicles

Identifiers

PMID32051811
PMCPMC7015464
OpenAlexW2955601696

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.