Evidence map›Paper›PMID 32051758›Full record

ReviewF1000Research2020

New insights into the pathogenesis of leprosy: contribution of subversion of host cell metabolism to bacterial persistence, disease progression, and transmission.

Cristiana Santos de Macedo, Flavio Alves Lara, Roberta Olmo Pinheiro, Veronica Schmitz, Marcia de Berrêdo-Pinho, Geraldo Moura Pereira, Maria Cristina Vidal Pessolani

Open access · goldAbstract readReview
In one paragraph

Review in F1000Research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
0.6field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 38 citations in OpenAlex.

  1. Lipid metabolism in homeostasis and disease.Signal transduction and targeted therapy · 2026
    Review
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Adenosine AFrontiers in pharmacology · 2024
    Article
  8. Article
  9. Review
  10. Modulation of the Response toFrontiers in microbiology · 2022
    Review
  11. Review
  12. Review
  13. Insights intoProteomes · 2021
    Review
  14. Review
  15. Article
  16. Review
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Cristiana Santos de MacedoCenter for Technological Development in Health (CDTS), Oswaldo Cruz Foundation (FIOCRUZ), Rio de Janeiro, 21040-361, Brazil.ORCID 0000-0002-5637-9756
Flavio Alves LaraLaboratory of Cellular Microbiology, Oswaldo Cruz Institute (IOC), Oswaldo Cruz Foundation (FIOCRUZ), Rio de Janeiro, 21040-360, Brazil.
Roberta Olmo PinheiroLeprosy Laboratory, Oswaldo Cruz Institute (IOC), Oswaldo Cruz Foundation (FIOCRUZ), Rio de Janeiro, 21040-360, Brazil.
Veronica SchmitzLeprosy Laboratory, Oswaldo Cruz Institute (IOC), Oswaldo Cruz Foundation (FIOCRUZ), Rio de Janeiro, 21040-360, Brazil.ORCID 0000-0002-0865-133X
Marcia de Berrêdo-PinhoLaboratory of Cellular Microbiology, Oswaldo Cruz Institute (IOC), Oswaldo Cruz Foundation (FIOCRUZ), Rio de Janeiro, 21040-360, Brazil.
Geraldo Moura Pereira *Laboratory of Cellular Microbiology, Oswaldo Cruz Institute (IOC), Oswaldo Cruz Foundation (FIOCRUZ), Rio de Janeiro, 21040-360, Brazil.ORCID 0000-0001-6896-5376
Maria Cristina Vidal Pessolani *Laboratory of Cellular Microbiology, Oswaldo Cruz Institute (IOC), Oswaldo Cruz Foundation (FIOCRUZ), Rio de Janeiro, 21040-360, Brazil.ORCID 0000-0003-3064-8759
Fundação Oswaldo Cruz · BR

Funding

The role of Tregs and lipid mediators in the progression of Mycobacterium leprae infection to active diseaseR01AI129835 · NIAID · FUNDACAO OSWALDO CRUZ · PI PESSOLANI, MARIA CRISTINA VIDAL · 2017 to 2021
$721k
NIAID NIH HHS R01 AI129835
6 · The paper itself

Abstract

Chronic infection by the obligate intracellular pathogen

Indexed as

LeprosyCholesterolDisease ProgressionHumansMycobacterium lepraeSchwann CellsCholesteroldisease toleranceimmune responseLeprosylipidsmetabolismmycobacteriumregulatory T cells

Identifiers

PMID32051758
PMCPMC6996526
OpenAlexW3003774576

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.