Evidence map›Paper›PMID 32051748›Full record

ArticleAmerican journal of translational research2020

Topical application of temperature-sensitive caerin 1.1 and 1.9 gel inhibits TC-1 tumor growth in mice.

Bowei Ma, Jianwei Yuan, Shu Chen, Kunsong Huang, Qianbo Wang, Jianchun Ma, Ruoting Lin, Lu Zhang, Yingying Zhou, Tianfang Wang and 6 more

Open access · greenAbstract read
In one paragraph

Article in American journal of translational research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 23 citations in OpenAlex.

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  9. Frontiers in oncology · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 3 institutions in 2 countries.

Bowei MaThe First Affiliated Hospital/Clinical Medical School, Department of Nuclear Medicine, Guangdong Pharmaceutical University Guangzhou 510080, Guangdong, China.
Jianwei YuanThe First Affiliated Hospital/Clinical Medical School, Department of Nuclear Medicine, Guangdong Pharmaceutical University Guangzhou 510080, Guangdong, China.
Shu ChenCancer Research Institute, Foshan First People's Hospital Foshan 528000, Guangdong, China.
Kunsong HuangThe First Affiliated Hospital/Clinical Medical School, Department of Nuclear Medicine, Guangdong Pharmaceutical University Guangzhou 510080, Guangdong, China.
Qianbo WangThe First Affiliated Hospital/Clinical Medical School, Department of Nuclear Medicine, Guangdong Pharmaceutical University Guangzhou 510080, Guangdong, China.
Jianchun MaThe First Affiliated Hospital/Clinical Medical School, Department of Nuclear Medicine, Guangdong Pharmaceutical University Guangzhou 510080, Guangdong, China.
Ruoting LinThe First Affiliated Hospital/Clinical Medical School, Department of Nuclear Medicine, Guangdong Pharmaceutical University Guangzhou 510080, Guangdong, China.
Lu ZhangThe First Affiliated Hospital/Clinical Medical School, Department of Nuclear Medicine, Guangdong Pharmaceutical University Guangzhou 510080, Guangdong, China.
Yingying ZhouThe First Affiliated Hospital/Clinical Medical School, Department of Nuclear Medicine, Guangdong Pharmaceutical University Guangzhou 510080, Guangdong, China.
Tianfang WangGenecology Research Centre, University of Sunshine Coast Maroochydore DC, QLD 4558, Australia.
Shelley F WaltonInflammation and Healing Research Cluster, School of Health and Sport Sciences, University of Sunshine Coast Maroochydore DC, QLD 4558, Australia.
Xuan PanThe First Affiliated Hospital/Clinical Medical School, Department of Nuclear Medicine, Guangdong Pharmaceutical University Guangzhou 510080, Guangdong, China.
Guoqiang ChenCancer Research Institute, Foshan First People's Hospital Foshan 528000, Guangdong, China.
Yuejian WangCancer Research Institute, Foshan First People's Hospital Foshan 528000, Guangdong, China.
Guoying NiThe First Affiliated Hospital/Clinical Medical School, Department of Nuclear Medicine, Guangdong Pharmaceutical University Guangzhou 510080, Guangdong, China.
Xiaosong LiuThe First Affiliated Hospital/Clinical Medical School, Department of Nuclear Medicine, Guangdong Pharmaceutical University Guangzhou 510080, Guangdong, China.
Guangdong Pharmaceutical University · CNUniversity of the Sunshine Coast · AUFirst People's Hospital of Foshan · CN

Funding

CAREER LEADERSHIP AWARDK07AG001003 · NIA · EMORY UNIVERSITY · PI OUSLANDER, JOSEPH G. · 2000 to 2004
$540k
NIA NIH HHS K07 AG001003
6 · The paper itself

Abstract

Genital warts, which are one of the most common sexually transmitted diseases (STDs), result from persistent infection with human papillomavirus (HPV), especially subtypes 6 or 11. Topical application of 5% imiquimod cream is currently recommended as a first-line treatment choice for genital warts, but the clearance and patient compliance rates remain less than sufficient. In the current study, we developed a temperature-sensitive gel that contains the host-defense peptides caerin 1.1 and 1.9, which were originally isolated from Australian tree frogs of the genus

Indexed as

Caerin peptidesgelgenital warts

Identifiers

PMID32051748
PMCPMC7013226
OpenAlexW3009971296

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.