Evidence map›Paper›PMID 32051724›Full record

ArticleArchives of medical science : AMS2020

The effects of hyperbilirubinaemia on synaptic plasticity in the dentate gyrus region of the rat hippocampus

Li Yang, De Wu, Baotian Wang, Xiaosong Bu, Jing Zhu, Jiulai Tang

Open access · goldAbstract read
In one paragraph

Article in Archives of medical science : AMS, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.1field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
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  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Li YangDepartment of Paediatrics, The First Affiliated Hospital of Anhui Medical University, Hefei, China.
De WuDepartment of Paediatrics, The First Affiliated Hospital of Anhui Medical University, Hefei, China.
Baotian WangDepartment of Paediatrics, The First Affiliated Hospital of Anhui Medical University, Hefei, China.
Xiaosong BuDepartment of Paediatrics, The First Affiliated Hospital of Anhui Medical University, Hefei, China.
Jing ZhuDepartment of Paediatrics, The First Affiliated Hospital of Anhui Medical University, Hefei, China.
Jiulai TangDepartment of Paediatrics, The First Affiliated Hospital of Anhui Medical University, Hefei, China.
First Affiliated Hospital of Anhui Medical University · CNAnhui Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe aim of our study is to investigate the effect of hyperbilirubinaemia on synaptic plasticity in the dentate gyrus (DG) region of the rat hippocampus. MATERIAL AND

methodsSeven-day-old healthy Sprague Dawley (SD) rats were randomly divided into a control group and an experiment group (

resultsCompared with that in the control rats, the current-voltage curves of both EPSP slope and PS amplitude in the experimental rats were significantly depressed. The average peak facilitation was 187 ±16% in the control and 164 ±18% in the experiment group (

conclusionsThese findings suggest that hyperbilirubinaemia could induce impairment of synaptic plasticity in the rat DG area

Indexed as

dentate gyrushippocampushyperbilirubinaemiasynaptic plasticity

Identifiers

PMID32051724
PMCPMC6963152
OpenAlexW2990764572

What OpenQuestion holds

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LicenceCC BY-NC-SA
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.