Evidence map›Paper›PMID 32051530›Full record

ArticleLeukemia2020

Extracellular vesicles from myelodysplastic mesenchymal stromal cells induce DNA damage and mutagenesis of hematopoietic stem cells through miRNA transfer.

Mathieu Meunier, Audrey Guttin, Sarah Ancelet, David Laurin, Johanna Zannoni, Christine Lefebvre, Sylvie Tondeur, Virginie Persoons, Mylène Pezet, Karin Pernet-Gallay and 14 more

Abstract readLetter
PubMed Publisher
In one paragraph

Article in Leukemia, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Review
  5. Article
  6. Article
  7. Review
  8. Review
  9. Extracellular Vesicles in Myeloid Neoplasms.International journal of molecular sciences · 2022
    Review
  10. Regulation of Malignant Myeloid Leukemia by Mesenchymal Stem Cells.Frontiers in cell and developmental biology · 2022
    Review
  11. Article
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors.

Mathieu MeunierDepartment of Hematology, CHU Grenoble Alpes, Grenoble, France. mmeunier2@chu-grenoble.fr.
Audrey GuttinGrenoble Institut des Neurosciences, INSERM U836, Grenoble Alpes University, Grenoble, France.
Sarah AnceletCNRS UMR 5309, INSERM, U1209, Université Grenoble Alpes, Institute for Advanced Bioscience, 38700, Grenoble, France.
David LaurinCNRS UMR 5309, INSERM, U1209, Université Grenoble Alpes, Institute for Advanced Bioscience, 38700, Grenoble, France.
Johanna ZannoniDepartment of Hematology, CHU Grenoble Alpes, Grenoble, France.
Christine LefebvreLaboratoire de Génétique des hémopathies, CHU Grenoble Alpes, Grenoble, France.
Sylvie TondeurLaboratoire de Génétique des hémopathies, CHU Grenoble Alpes, Grenoble, France.
Virginie PersoonsUnité de Thérapie et d'Ingénierie Cellulaire, EFS Auvergne Rhône Alpes et UF Génétique moléculaire et maladie héréditaire et oncologie, CHUGA, Grenoble, France.
Mylène PezetCNRS UMR 5309, INSERM, U1209, Université Grenoble Alpes, Institute for Advanced Bioscience, 38700, Grenoble, France.
Karin Pernet-GallayGrenoble Institut des Neurosciences, Plateforme de Microscopie électronique, Grenoble Alpes University, Grenoble, France.
Florent ChuffartCNRS UMR 5309, INSERM, U1209, Université Grenoble Alpes, Institute for Advanced Bioscience, 38700, Grenoble, France.
Sophie RousseauxCNRS UMR 5309, INSERM, U1209, Université Grenoble Alpes, Institute for Advanced Bioscience, 38700, Grenoble, France.ORCID http://orcid.org/0000-0001-5246-5350
Quentin TestardCNRS UMR 5309, INSERM, U1209, Université Grenoble Alpes, Institute for Advanced Bioscience, 38700, Grenoble, France.
Julien ThevenonCNRS UMR 5309, INSERM, U1209, Université Grenoble Alpes, Institute for Advanced Bioscience, 38700, Grenoble, France.
Claire JouzierDepartment of Hematology, CHU Grenoble Alpes, Grenoble, France.
Jean-François DeleuzeCentre National de Génotypage, Institut de Génomique, Evry and Centre d'Etude du Polymorphisme Humain, 2 rue Gaston Crémieux, 91000, Paris, France.
Karine LaulagnierGrenoble Institut des Neurosciences, INSERM U836, Grenoble Alpes University, Grenoble, France.
Rémy SadoulGrenoble Institut des Neurosciences, INSERM U836, Grenoble Alpes University, Grenoble, France.
Christine ChatellardGrenoble Institut des Neurosciences, INSERM U836, Grenoble Alpes University, Grenoble, France.
Pierre HainautCNRS UMR 5309, INSERM, U1209, Université Grenoble Alpes, Institute for Advanced Bioscience, 38700, Grenoble, France.
Benoît PolackDepartment of Hematology, CHU Grenoble Alpes, Grenoble, France.
Jean-Yves CahnDepartment of Hematology, CHU Grenoble Alpes, Grenoble, France.
Jean-Paul IssartelGrenoble Institut des Neurosciences, INSERM U836, Grenoble Alpes University, Grenoble, France.
Sophie ParkDepartment of Hematology, CHU Grenoble Alpes, Grenoble, France. spark@chu-grenoble.fr.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

DNA DamageMutagenesisDEAD-box RNA HelicasesExtracellular VesiclesHematopoietic Stem CellsHumansMesenchymal Stem CellsMicroRNAsMyelodysplastic SyndromesRibonuclease IIIDEAD-box RNA HelicasesDICER1 protein, humanMicroRNAsRibonuclease III

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.