Evidence map›Paper›PMID 32051309›Full record

ArticleBMJ open2020

Bone health in bipolar disorder: a study protocol for a case-control study in Australia.

Lana J Williams, Amanda L Stuart, Michael Berk, Sharon L Brennan-Olsen, Jason M Hodge, Stephanie Cowdery, Vinoomika Chandrasekaran, Julie A Pasco

Abstract read
In one paragraph

Article in BMJ open, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Pain in women with and without bipolar spectrum disorder.Frontiers in global women's health · 2025
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Lana J WilliamsSchool of Medicine, Deakin University, Geelong, Victoria, Australia l.williams@deakin.edu.au.ORCID 0000-0002-1377-1272
Amanda L StuartSchool of Medicine, Deakin University, Geelong, Victoria, Australia.
Michael BerkSchool of Medicine, Deakin University, Geelong, Victoria, Australia.
Sharon L Brennan-OlsenDepartment of Medicine-Western Health, The University of Melbourne, St Albans, Victoria, Australia.ORCID 0000-0003-3269-5401
Jason M HodgeSchool of Medicine, Deakin University, Geelong, Victoria, Australia.
Stephanie CowderySchool of Medicine, Deakin University, Geelong, Victoria, Australia.
Vinoomika ChandrasekaranSchool of Medicine, Deakin University, Geelong, Victoria, Australia.ORCID 0000-0002-3910-3248
Julie A PascoSchool of Medicine, Deakin University, Geelong, Victoria, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionLittle is known about the bone health of adults with bipolar disorder, aside from evidence purporting bone deficits among individuals with other mental illnesses, or those taking medications commonly used in bipolar disorder. In this paper, we present the methodology of a case-control study which aims to examine the role of bipolar disorder as a risk factor for bone fragility. METHODS AND ANALYSIS: Men and women with bipolar disorder (~200 cases) will be recruited and compared with participants with no history of bipolar disorder (~1500 controls) from the Geelong Osteoporosis Study. Both cases and controls will be drawn from the Barwon Statistical Division, south-eastern Australia. The Structured Clinical Interview for DSM-IV-TR Research Version, Non-patient edition is the primary diagnostic instrument, and psychiatric symptomatology will be assessed using validated rating scales. Demographic information and detailed lifestyle data and medical history will be collected via comprehensive questionnaires. Participants will undergo dual energy X-ray absorptiometry scans and other clinical measures to determine bone and body composition. Blood samples will be provided after an overnight fast and stored for batch analysis. ETHICS AND DISSEMINATION: Ethics approval has been granted from Barwon Health Research Ethics Committee. Participation in the study is voluntary. The study findings will be disseminated via peer-reviewed publications, conference presentations and reports to the funding body.

Indexed as

Research DesignAbsorptiometry, PhotonAdultAgedAged, 80 and overAustraliaBipolar DisorderBone and BonesBone DensityCase-Control StudiesFemaleHumansMaleMiddle AgedOsteoporosisYoung Adultbipolar disorderbone mineral densityhealthlifestylemedical conditionsosteoporosis

Identifiers

PMID32051309
PMCPMC7044863

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.