Evidence map›Paper›PMID 32051276›Full record

ReviewJournal of virology2020

Mus musculus Papillomavirus 1: a New Frontier in Animal Models of Papillomavirus Pathogenesis.

Megan E Spurgeon, Paul F Lambert

Open access · greenAbstract readReview
In one paragraph

Review in Journal of virology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed
3.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 46 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Article
  6. Mouse Papillomavirus Outbreak in a Research Facility.Journal of the American Association for Laboratory Animal Science : JAALAS · 2025
    Article
  7. Article
  8. Article
  9. Article
  10. Papillomavirus-like particles as vectors forMolecular therapy. Nucleic acids · 2025
    Article
  11. Article
  12. Article
  13. Review
  14. Deficiency inJournal of virology · 2024
    Article
  15. Article
  16. Article
  17. Review
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Megan E SpurgeonMcArdle Laboratory for Cancer Research, Department of Oncology, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, Wisconsin, USA megan.spurgeon@wisc.edu.
Paul F LambertMcArdle Laboratory for Cancer Research, Department of Oncology, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, Wisconsin, USA.
University of Wisconsin–Madison · US

Funding

Visualizing EBV and HCMV DNA Dynamics During InfectionP01CA022443 · NCI · UNIVERSITY OF WISCONSIN-MADISON · PI WILLIAM M. SUGDEN · 1985 to 2026
$53.1M
Project 4: Role of Receptor Tyrosine Kinase AXL in HNSCC Therapy ResistanceP50DE026787 · NIDCR · UNIVERSITY OF WISCONSIN-MADISON · PI HARARI, PAUL M · 2016 to 2020
$10.8M
Defining Drivers of HPV-associated CarcinogenesisR35CA210807 · NCI · UNIVERSITY OF WISCONSIN-MADISON · PI Paul F. Lambert · 2017 to 2026
$9.2M
Mouse Model of Human Papillomavirus PathogenesisR01CA228543 · NCI · TUFTS UNIVERSITY BOSTON · PI LAMBERT, PAUL F., MUNGER, KARL · 2019 to 2023
$2.3M
Small DNA Tumor Viruses and Human CancerR50CA211246 · NCI · UNIVERSITY OF WISCONSIN-MADISON · PI SPURGEON, MEGAN E · 2016 to 2020
$644k
NCI NIH HHS P01 CA022443NCI NIH HHS R01 CA228543NCI NIH HHS R35 CA210807NCI NIH HHS R50 CA211246NIDCR NIH HHS P50 DE026787
6 · The paper itself

Abstract

Animal models of viral pathogenesis are essential tools in human disease research. Human papillomaviruses (HPVs) are a significant public health issue due to their widespread sexual transmission and oncogenic potential. Infection-based models of papillomavirus pathogenesis have been complicated by their strict species and tissue specificity. In this Gem, we discuss the discovery of a murine papillomavirus, Mus musculus papillomavirus 1 (MmuPV1), and how its experimental use represents a major advancement in models of papillomavirus-induced pathogenesis/carcinogenesis, and their transmission.

Indexed as

AnimalsCarcinogenesisDisease Models, AnimalMicePapillomaviridaePapillomavirus Infectionsanimal modelshuman papillomavirusMmuPV1murine papillomaviruspapillomavirusviral oncologyviral pathogenesis

Identifiers

PMID32051276
PMCPMC7163119
OpenAlexW3005873106

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.