ArticleJournal of virology2020
Modified Sialic Acids on Mucus and Erythrocytes Inhibit Influenza A Virus Hemagglutinin and Neuraminidase Functions.
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Article in Journal of virology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.
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42citing papers in PubMed
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Who cites it
42 citing papers in PubMed.
- Multiscale structural evolution of proline-rich protein genes shapes primate salivary defenses.Molecular biology and evolution · 2026Article
- Defined O-acetylated Neu5Ac substrates reveal position-specific preferences of gut bacterial sialidases.Glycobiology · 2026Article
- Receptor profiling and growth assessment of influenza A virus in porcine mammary and non-mammary tissues and derived cells.Journal of virology · 2026Article
- The receptor landscape of influenza A viruses.Journal of virology · 2026Review
- Genome-wide CRISPR screen identifies STK11 as a critical regulator of sialic acid clusters important for influenza A virus attachment.Journal of advanced research · 2026Article
- Biosynthetic and genetic pathways related to sialic acid metabolism.The Journal of biological chemistry · 2026Review
- Evolutionary Balancing of Genetic Consequence and Innovation in Mammals Through Variable Number Tandem Repeats.Genome biology and evolution · 2026Review
- Sialylation and fucosylation of mucin-type glycopeptides using recombinant glycosyltransferases.Methods in enzymology · 2026Article
- Human coronavirus HKU1 neutralization by glycan receptor mimicry.bioRxiv : the preprint server for biology · 2025Article
- Saliva Protein Genes in Humans were Shaped During Primate Evolution.Genome biology and evolution · 2025Article
- Discovery and characterization of vertebrate sialoglycan-binding proteins.Seminars in immunology · 2025Review
- Loss of sialic acid side-chainProceedings of the National Academy of Sciences of the United States of America · 2025Article
- Cell binding, uptake, and infection of influenza A virus using recombinant antibody-based receptors.Journal of virology · 2025Article
- Extended receptor repertoire of an adenovirus associated with human obesity.PLoS pathogens · 2025Article
- The mammary glands of cows abundantly display receptors for circulating avian H5 viruses.Journal of virology · 2024Article
- Synthetic Sialosides Terminated with 8-N-Substituted Sialic Acid as Selective Substrates for Sialidases from Bacteria and Influenza Viruses.Angewandte Chemie (International ed. in English) · 2024Article
- Review
- Influenza D virus utilizes both 9-Journal of virology · 2024Article
- Emergence of saliva protein genes in the secretory calcium-binding phosphoprotein (SCPP) locus and accelerated evolution in primates.bioRxiv : the preprint server for biology · 2024Article
- Insights into the Structure, Metabolism, Biological Functions and Molecular Mechanisms of Sialic Acid: A Review.Foods (Basel, Switzerland) · 2023Review
Corrections and comments
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Authors and funding
15 authors.
Karen N BarnardBaker Institute for Animal Health, Department of Microbiology and Immunology, College of Veterinary Medicine, Cornell University, Ithaca, New York, USA.ORCID 0000-0001-6283-4543
Brynn K Alford-LawrenceBaker Institute for Animal Health, Department of Microbiology and Immunology, College of Veterinary Medicine, Cornell University, Ithaca, New York, USA.
David W BuchholzDepartment of Microbiology and Immunology, College of Veterinary Medicine, Cornell University, Ithaca, New York, USA.
Brian R WasikBaker Institute for Animal Health, Department of Microbiology and Immunology, College of Veterinary Medicine, Cornell University, Ithaca, New York, USA.ORCID 0000-0001-5442-3883
Justin R LaClairBaker Institute for Animal Health, Department of Microbiology and Immunology, College of Veterinary Medicine, Cornell University, Ithaca, New York, USA.
Hai YuDepartment of Chemistry, University of California-Davis, Davis, California, USA.
Rebekah HonceDepartment of Infectious Diseases, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.
Stefan RuhlDepartment of Oral Biology, University at Buffalo, Buffalo, New York, USA.
Petar PajicDepartment of Oral Biology, University at Buffalo, Buffalo, New York, USA.
Erin K DaugherityCenter for Animal Resources and Education, Cornell University, Ithaca, New York, USA.
Xi ChenDepartment of Chemistry, University of California-Davis, Davis, California, USA.
Stacey L Schultz-CherryDepartment of Infectious Diseases, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.
Hector C AguilarDepartment of Microbiology and Immunology, College of Veterinary Medicine, Cornell University, Ithaca, New York, USA.
Ajit VarkiGlycobiology Research and Training Center, University of California, San Diego, California, USA.
Colin R ParrishBaker Institute for Animal Health, Department of Microbiology and Immunology, College of Veterinary Medicine, Cornell University, Ithaca, New York, USA crp3@cornell.edu.ORCID 0000-0002-1836-6655
Funding
Microbial Recognition of Sialic Acid Diversity in the Salivary ProteomeR01DE019807 · NIDCR · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI RUHL, STEFAN HANS-KLAUS · 2010 to 2022
$4.7MMechanisms of Nipah virus fusion and entryR01AI109022 · NIAID · WASHINGTON STATE UNIVERSITY · PI AGUILAR-CARRENO, HECTOR · 2014 to 2024
$4.3MThe Evolutionary and Biological Bases of Host Switching in VirusesR01GM080533 · NIGMS · PENNSYLVANIA STATE UNIVERSITY, THE · PI PARRISH, COLIN R. · 2007 to 2019
$4.1MSupplement: Exploring the biology of O-acetyl sialic acids using stable synthetic mimicsR01AI130684 · NIAID · UNIVERSITY OF CALIFORNIA AT DAVIS · PI CHEN, XI, VARKI, AJIT P · 2017 to 2020
$2.3MSialoglycan-Recognizing Probes for Defining Sialoglycomes in Biological SystemsU01CA199792 · NCI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI VARKI, AJIT P · 2015 to 2017
$1.9MHARNESSING THE ORAL MICROBIOME TO CREATE NOVEL GLYCAN-BINDING PROBESU01CA221244 · NCI · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI RUHL, STEFAN HANS-KLAUS, SULLAM, PAUL M. · 2017 to 2019
$1.4MIdentifying potent and broadly-neutralizing henipaviral antigens and epitopesR21AI142377 · NIAID · CORNELL UNIVERSITY · PI AGUILAR-CARRENO, HECTOR · 2019 to 2020
$416kEffects of Commons Sialic Acid Modifications on Virus Binding and InfectionR21AI142297 · NIAID · CORNELL UNIVERSITY · PI PARRISH, COLIN R. · 2019 to 2020
$415kNCI NIH HHS U01 CA199792NCI NIH HHS U01 CA221244NIAID NIH HHS HHSN272201400008CNIAID NIH HHS R01 AI109022NIAID NIH HHS R01 AI130684NIAID NIH HHS R21 AI142297NIDCR NIH HHS R01 DE019807NIGMS NIH HHS R01 GM080533
Abstract
Sialic acids (Sia) are the primary receptors for influenza viruses and are widely displayed on cell surfaces and in secreted mucus. Sia may be present in variant forms that include
Indexed as
A549 CellsAnimalsDogsErythrocytesFemaleHemagglutinin Glycoproteins, Influenza VirusHemagglutininsHumansInfluenza A virusInfluenza, HumanMadin Darby Canine Kidney CellsMaleMiceMixed Function OxygenasesMucusN-Acetylneuraminic AcidCMPacetylneuraminate monooxygenaseHemagglutinin Glycoproteins, Influenza VirusHemagglutininsMixed Function OxygenasesN-Acetylneuraminic AcidNeuraminidaseO-acetyl sialic acidReceptors, Virusinfluenzamucussialic acids
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.