ArticleThe British journal of ophthalmology2020
Comparison of OCT angiography in children with a history of intravitreal injection of ranibizumab versus laser photocoagulation for retinopathy of prematurity.
Article in The British journal of ophthalmology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07427719 (Children Treated for Retinopathy of Prematurity - Study of Visual Function and Retinal Structure), which is not on this map. Cited by 16 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Children Treated for Retinopathy of Prematurity - Study of Visual Function and Retinal Structure
Who cites it
16 citing papers in PubMed, 21 citations in OpenAlex.
- Macular development in preterm twins with and without retinopathy of prematurity: an OCT angiography study from the Shenzhen prematurity eye study.European journal of medical research · 2026Article
- Prediction Models for Recurrence of Retinopathy of Prematurity after Intravitreal Ranibizumab or Laser Photocoagulation Treatment: A Multicenter Cohort Study.Ophthalmology and therapy · 2026Article
- Eyecare-cloud: an innovative electronic medical record cloud platform for pediatric research and clinical care.The EPMA journal · 2024Article
- Vascular imaging findings in retinopathy of prematurity.Acta ophthalmologica · 2024Review
- A fundus image dataset for intelligent retinopathy of prematurity system.Scientific data · 2024Article
- Comparison of long-term treatment outcomes of laser and anti-VEGF therapy in retinopathy of prematurity: a multicentre study from J-CREST group.Eye (London, England) · 2023Article
- Efficacy of four anti-vascular endothelial growth factor agents and laser treatment for retinopathy of prematurity: A network meta-analysis.Biomolecules & biomedicine · 2023Article
- Visual field after anti-vascular endothelial growth factor therapy and laser treatment for retinopathy of prematurity.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2023Article
- Optical Coherence Tomography and Optical Coherence Tomography Angiography in Pediatric Retinal Diseases.Diagnostics (Basel, Switzerland) · 2023Review
- Evaluation of macular microvascular structure with optical coherence tomography angiography in children with history of treatment for retinopathy of prematurity.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2023Article
- Retinal and peripapillary vascular deformations in prematurely born children aged 4-12 years with a history of retinopathy of prematurity.Scientific reports · 2023Article
- Insights into the developing fovea revealed by imaging.Progress in retinal and eye research · 2022Review
- Morphology and Vessel Density of the Macula in Preterm Children Using Optical Coherence Tomography Angiography.Journal of clinical medicine · 2022Article
- Preservation of the Foveal Avascular Zone in Achromatopsia Despite the Absence of a Fully Formed Pit.Investigative ophthalmology & visual science · 2020Article
- An Update on Anti-Vascular Endothelial Growth Factor Treatment for Retinopathy of Prematurity.Journal of current ophthalmologyReview
- Multimodal Imaging, Tele-Education, and Telemedicine in Retinopathy of Prematurity.Middle East African journal of ophthalmologyReview
Corrections and comments
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Authors and funding
10 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo compare the foveal microvascular structure characteristics in children with a history of intravitreal injection of ranibizumab (IVR) versus laser photocoagulation (LP) for retinopathy of prematurity by optical coherence tomography angiography (OCTA).
methodsIn this cross-sectional study, a total of 17 children (28 eyes) underwent IVR and 20 children (37 eyes) underwent LP were recruited. The age of doing OCTA examination of the two groups are 5.4±1.1 years and 6.3±1.8 years, respectively (p=0.07). Spectral-domain OCTA was performed for all the eyes with a scan size of 3×3 mm. The data of the superficial retinal layer were analysed. The foveal avascular zone (FAZ) and vessel density (including vessel length density (VLD) and perfusion density (PD)) were measured using the software of OCTA (Cirrus AngioPlex 5000, Carl Zeiss, Meditec, Dubin, California, USA). The central foveal thicknesses (CFT) were measured by cross-sectional OCT.
resultsIn the central fovea, the retinal VLD and PD of patients with IVR were 13.82±2.99 mm/mm
conclusionThe IVR might contribute to microvascular changes in the macular zone, such as reducing the central foveal VLD and PD, while the LP might contribute to microstructural changes, such as smaller FAZ and thicker CFT.
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