Evidence map›Paper›PMID 32050977›Full record

ArticleDiagnostic pathology2020

Markers of immune activation: novel biomarkers to predict the early-warning indicator of patients with papillary thyroid carcinoma.

Hongsheng Lu, Lihong Zhang, Yuechu Dai, Yanyun Ruan, Xuequan Cao, Xiaobo Cai, Sihan Ruan, Qi Chen

Open access · goldAbstract read
In one paragraph

Article in Diagnostic pathology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.1field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. LncRNA ABHD11-AS1 promotes tumor progression in papillary thyroid carcinoma by regulating EPS15L1/EGFR signaling pathway.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2022
    Article
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  7. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Hongsheng LuDepartment of pathology, Taizhou Central Hospital (Taizhou University Hospital), Taizhou, Zhejiang, People's Republic of China.
Lihong ZhangDepartment of Clinical Laboratory Center, Shaoxing People's Hospital, Shaoxing, Zhejiang, People's Republic of China.
Yuechu DaiDepartment of Surgical Oncology, Taizhou Central Hospital (Taizhou University Hospital), Taizhou, Zhejiang, People's Republic of China.
Yanyun RuanDepartment of Central Laboratory, Taizhou Central Hospital (Taizhou University Hospital), Taizhou, 318000, Zhejiang, People's Republic of China.
Xuequan CaoDepartment of pathology, Taizhou Central Hospital (Taizhou University Hospital), Taizhou, Zhejiang, People's Republic of China.
Xiaobo CaiDepartment of pathology, Taizhou Central Hospital (Taizhou University Hospital), Taizhou, Zhejiang, People's Republic of China.
Sihan RuanDepartment of Central Laboratory, Taizhou Central Hospital (Taizhou University Hospital), Taizhou, 318000, Zhejiang, People's Republic of China.
Qi ChenDepartment of Central Laboratory, Taizhou Central Hospital (Taizhou University Hospital), Taizhou, 318000, Zhejiang, People's Republic of China. chenqi7997@163.com.ORCID http://orcid.org/0000-0002-0640-6859
Taizhou Central Hospital · CNShaoxing People's Hospital · CN

Funding

Zhejiang Provincial Natural Science Foundation LGD20H160004Zhejiang Provincial Natural Science Foundation LGF20H160029
6 · The paper itself

Abstract

backgroundPapillary thyroid carcinoma (PTC) is an indolent tumor that is exploding with increasing thyroid nodules (TN). Environmental carcinogens, lifestyle changes increased the incidence of thyroid carcinoma. With the development of B-ultrasound imaging, more and more thyroid cancer has been found. There has been a debate about whether thyroid cancer is overtreated.

methodsThe expression of T cell subsets and plasma cytokines in 191 patients, including 79 patients with PTC (PTC group), 58 patients with thyroid nodules (TN group) and 54 healthy individuals (HP group) were analyzed by flow cytometry.

resultsHigh levels of natural killer cells (NK) were detected in PTC and TN groups than in HP group. High activities of CD8

conclusionsThese results indicated that CD8

Indexed as

AdultAgedBiomarkers, TumorCarcinomaCarcinoma, PapillaryFemaleHumansLymphatic MetastasisMaleMiddle AgedThyroid Cancer, PapillaryThyroid NeoplasmsThyroid NoduleBiomarkers, TumorBiomarkersDiagnostic performanceImmune activationLymph node metastasisPapillary thyroid carcinomaThyroid nodules

Identifiers

PMID32050977
PMCPMC7017425
OpenAlexW3006960899

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.