Evidence map›Paper›PMID 32050905›Full record

ArticleBMC bioinformatics2020

GsmPlot: a web server to visualize epigenome data in NCBI.

Jia Li, Yue Yin, Mutian Zhang, Jie Cui, Zhenhai Zhang, Zhiyong Zhang, Deqiang Sun

Abstract read
In one paragraph

Article in BMC bioinformatics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Trial
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jia LiCenter for Epigenetics & Disease Prevention, Institute of Biosciences and Technology, Texas A&M University College of Medicine, Houston, TX, 77030, USA.
Yue YinCenter for Epigenetics & Disease Prevention, Institute of Biosciences and Technology, Texas A&M University College of Medicine, Houston, TX, 77030, USA.
Mutian ZhangCenter for Epigenetics & Disease Prevention, Institute of Biosciences and Technology, Texas A&M University College of Medicine, Houston, TX, 77030, USA.
Jie CuiKey Laboratory of Special Pathogens and Biosafety, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, 430071, China.
Zhenhai ZhangCenter for Bioinformatics, School of Basic Medical Sciences, Southern Medical University, Guangzhou, China.
Zhiyong ZhangThe Third Affiliated Hospital of Guangzhou Medical University, Guangzhou, China. mr.zhiyong@gmail.com.
Deqiang SunCenter for Epigenetics & Disease Prevention, Institute of Biosciences and Technology, Texas A&M University College of Medicine, Houston, TX, 77030, USA. dsun@tamu.edu.

Funding

Cancer Prevention and Research Institute of Texas RP180131
6 · The paper itself

Abstract

backgroundEpigenetic regulation is essential in regulating gene expression across a variety of biological processes. Many high-throughput sequencing technologies have been widely used to generate epigenetic data, such as histone modification, transcription factor binding sites, DNA modifications, chromatin accessibility, and etc. A large scale of epigenetic data is stored in NCBI Gene Expression Omnibus (GEO). However, it is a great challenge to reanalyze these large scale and complex data, especially for researchers who do not specialize in bioinformatics skills or do not have access to expensive computational infrastructure.

resultsGsmPlot can simply accept GSM IDs to automatically download NCBI data or can accept user's private bigwig files as input to plot the concerned data on promoters, exons or any other user-defined genome locations and generate UCSC visualization tracks. By linking public data repository and private data, GsmPlot can spark data-driven ideas and hence promote the epigenetic research.

conclusionsGsmPlot web server allows convenient visualization and efficient exploration of any NCBI epigenetic data in any genomic region without need of any bioinformatics skills or special computing resources. GsmPlot is freely available at https://gsmplot.deqiangsun.org/.

Indexed as

Epigenesis, GeneticEpigenomeSoftwareChromatinComputer GraphicsDatabases, GeneticDNA MethylationGenomicsHistone CodeInternetNational Library of Medicine (U.S.)Promoter Regions, GeneticUnited StatesChromatinEpigeneticsGsmPlotNCBIVisualizationWebserver

Identifiers

PMID32050905
PMCPMC7017537

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.