Evidence map›Paper›PMID 32050841›Full record

ArticleBioengineered2020

MiR-211 protects cerebral ischemia/reperfusion injury by inhibiting cell apoptosis.

Wenyi Liu, Yuanqing Miao, Lin Zhang, Xiaolin Xu, Qi Luan

Open access · goldAbstract read
In one paragraph

Article in Bioengineered, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed, 1 pooled it
4.5field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

44 citing papers in PubMed, 1 synthesis or guideline pooled it, 75 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Wenyi LiuDepartment of Anesthesia, The Affiliated Hospital of Qingdao University, Qingdao, Shandong, China.
Yuanqing MiaoDepartment of Medical Network Information Center, The Affiliated Hospital of Qingdao University, Qingdao, Shandong, China.
Lin ZhangDepartment of Anesthesia, The Affiliated Hospital of Qingdao University, Qingdao, Shandong, China.
Xiaolin XuDepartment of Anesthesia, The Affiliated Hospital of Qingdao University, Qingdao, Shandong, China.
Qi LuanDepartment of Anesthesia, The Affiliated Hospital of Qingdao University, Qingdao, Shandong, China.ORCID 0000-0001-6668-6584
Qingdao University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

MicroRNAs (miRNAs) have emerged as critical regulators of neuronal survival during cerebral ischemia/reperfusion injury. Accumulating evidence has shown that miR-211 plays a crucial role in regulating apoptosis and survival in various cell types. However, whether miR-211 is involved in regulating neuronal survival during cerebral ischemia/reperfusion injury remains unknown. In this study, we aimed to explore the biological role of miR-211 in regulating neuronal injury induced by oxygen-glucose deprivation/reoxygenation (OGD/R) and transient cerebral ischemia/reperfusion (I/R) injury

Indexed as

AnimalsApoptosisApoptosis Regulatory ProteinsBlotting, WesternBrainFlow CytometryIn Situ Nick-End LabelingMaleMice, Inbred C57BLMicroRNAsNeuronsPC12 CellsRatsReperfusion InjuryApoptosis Regulatory ProteinsBbc3 protein, ratMicroRNAsMirn211 microRNA, mouseMIRN211 microRNA, ratapoptosisIschemia/reperfusionMir-211oxygen-glucose deprivationP53-up-regulated modulator of apoptosis (PUMA)

Identifiers

PMID32050841
PMCPMC7039642
OpenAlexW3006485780

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.