Evidence map›Paper›PMID 32050579›Full record

ArticleInternational journal of molecular sciences2020

miR-128a Acts as a Regulator in Cardiac Development by Modulating Differentiation of Cardiac Progenitor Cell Populations.

Sarah C Hoelscher, Theresia Stich, Anne Diehm, Harald Lahm, Martina Dreßen, Zhong Zhang, Irina Neb, Zouhair Aherrahrou, Jeanette Erdmann, Heribert Schunkert and 8 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 18 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
  5. In-Depth Genomic Analysis: The New Challenge in Congenital Heart Disease.International journal of molecular sciences · 2024
    Review
  6. Review
  7. Cardiac microRNAs: diagnostic and therapeutic potential.Archives of medical science : AMS · 2023
    Article
  8. Review
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 7 institutions in 2 countries.

Sarah C HoelscherDepartment of Cardiovascular Surgery, German Heart Center Munich at the Technische Universität München, 80636 Munich, Germany.
Theresia StichDepartment of Cardiovascular Surgery, German Heart Center Munich at the Technische Universität München, 80636 Munich, Germany.
Anne DiehmDepartment of Cardiovascular Surgery, German Heart Center Munich at the Technische Universität München, 80636 Munich, Germany.
Harald LahmDepartment of Cardiovascular Surgery, German Heart Center Munich at the Technische Universität München, 80636 Munich, Germany.
Martina DreßenDepartment of Cardiovascular Surgery, German Heart Center Munich at the Technische Universität München, 80636 Munich, Germany.
Zhong ZhangDepartment of Cardiovascular Surgery, German Heart Center Munich at the Technische Universität München, 80636 Munich, Germany.
Irina NebDepartment of Cardiovascular Surgery, German Heart Center Munich at the Technische Universität München, 80636 Munich, Germany.
Zouhair AherrahrouInstitute for Cardiogenetics, University of Lübeck, 23562 Lübeck, Germany.
Jeanette ErdmannInstitute for Cardiogenetics, University of Lübeck, 23562 Lübeck, Germany.
Heribert SchunkertGerman Center for Cardiovascular Research (DZHK)-Partner Site Munich Heart Alliance, Biedersteiner Strasse 29, 80802 München, Germany.
Gianluca SantamariaMedical Department 1, Cardiology, Klinikum rechts der Isar, Technische Universität, 81675 Munich, Germany.ORCID 0000-0001-9284-7492
Giovanni CudaDepartment of Experimental and Clinical Medicine, Stem Cell Laboratory, Research Center of Advanced Biochemistry and Molecular Biology, University "Magna Graecia" of Catanzaro, Viale Europa, 88100 Catanzaro, Italy.ORCID 0000-0001-6313-1866
Ralf GilsbachInstitute of Experimental and Clinical Pharmacology and Toxicology, Faculty of Medicine, University of Freiburg, Albertstrasse 25, 79104 Freiburg, Germany.
Lutz HeinInstitute of Experimental and Clinical Pharmacology and Toxicology, Faculty of Medicine, University of Freiburg, Albertstrasse 25, 79104 Freiburg, Germany.ORCID 0000-0003-1297-0007
Rüdiger LangeDepartment of Cardiovascular Surgery, German Heart Center Munich at the Technische Universität München, 80636 Munich, Germany.
David HasselDepartment of Medicine III, Cardiology, Angiology, Pneumology, University Hospital Heidelberg, 69120 Heidelberg, Germany.
Markus KraneDepartment of Cardiovascular Surgery, German Heart Center Munich at the Technische Universität München, 80636 Munich, Germany.
Stefanie A DopplerDepartment of Cardiovascular Surgery, German Heart Center Munich at the Technische Universität München, 80636 Munich, Germany.
Deutsches Herzzentrum München · DEGerman Centre for Cardiovascular Research · DEGoethe University Frankfurt · DEHeidelberg University · DEMagna Graecia University · ITTUM Klinikum · DEUniversity of Freiburg · DE

Funding

Deutsche Forschungsgemeinschaft KR3770/11-1Deutsches Zentrum für Herz-Kreislaufforschung DZHK B 13-050ADeutsches Zentrum für Herz-Kreislaufforschung DZHK B 15-039SE
6 · The paper itself

Abstract

MicroRNAs (miRs) appear to be major, yet poorly understood players in regulatory networks guiding cardiogenesis. We sought to identify miRs with unknown functions during cardiogenesis analyzing the miR-profile of multipotent

Indexed as

Cell DifferentiationAnimalsCells, CulturedHomeobox Protein Nkx-2.5HumansMiceMicroRNAsMyocytes, CardiacPluripotent Stem CellsZebrafishHomeobox Protein Nkx-2.5MicroRNAsMirn128 microRNA, mousecardiac developmentcardiac progenitor cellsmicroRNAmiR-128Nkx2.5 cardiac enhancer

Identifiers

PMID32050579
PMCPMC7038042
OpenAlexW3004562503

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.