Evidence map›Paper›PMID 32050529›Full record

ArticleMolecules (Basel, Switzerland)2020

An Interpenetrating Alginate/Gelatin Network for Three-Dimensional (3D) Cell Cultures and Organ Bioprinting.

Qiuhong Chen, Xiaohong Tian, Jun Fan, Hao Tong, Qiang Ao, Xiaohong Wang

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed
4.3field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 83 citations in OpenAlex.

  1. Article
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  7. Hydrogel-Based Continuum Soft Robots.Gels (Basel, Switzerland) · 2025
    Review
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  11. Article
  12. Article
  13. Review
  14. Rising role of 3D-printing in delivery of therapeutics for infectious disease.Journal of controlled release : official journal of the Controlled Release Society · 2024
    Review
  15. Article
  16. Review
  17. Article
  18. Article
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  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Qiuhong ChenCenter of 3D Printing & Organ Manufacturing, School of Fundamental Sciences, China Medical University (CMU), No. 77 Puhe Road, Shenyang North New Area, Shenyang 110122, China.
Xiaohong TianCenter of 3D Printing & Organ Manufacturing, School of Fundamental Sciences, China Medical University (CMU), No. 77 Puhe Road, Shenyang North New Area, Shenyang 110122, China.
Jun FanCenter of 3D Printing & Organ Manufacturing, School of Fundamental Sciences, China Medical University (CMU), No. 77 Puhe Road, Shenyang North New Area, Shenyang 110122, China.
Hao TongCenter of 3D Printing & Organ Manufacturing, School of Fundamental Sciences, China Medical University (CMU), No. 77 Puhe Road, Shenyang North New Area, Shenyang 110122, China.
Qiang AoCenter of 3D Printing & Organ Manufacturing, School of Fundamental Sciences, China Medical University (CMU), No. 77 Puhe Road, Shenyang North New Area, Shenyang 110122, China.ORCID 0000-0002-1309-1971
Xiaohong WangCenter of 3D Printing & Organ Manufacturing, School of Fundamental Sciences, China Medical University (CMU), No. 77 Puhe Road, Shenyang North New Area, Shenyang 110122, China.
China Medical University · CN

Funding

the 2017 Discipline Promotion Project of China Medical University (CMU) 3110117049the 2018 Scientist Partners of China Medical University (CMU) and Shenyang Branch of Chinese Academy of Sciences (CAS) HZHB2018013the Key Research & Development Project of Liaoning Province 2018225082the National Natural Science Foundation of China (NSFC) 81571832 & 81271665 & 31600793 & 81571919
6 · The paper itself

Abstract

Crosslinking is an effective way to improve the physiochemical and biochemical properties of hydrogels. In this study, we describe an interpenetrating polymer network (IPN) of alginate/gelatin hydrogels (i.e., A-G-IPN) in which cells can be encapsulated for in vitro three-dimensional (3D) cultures and organ bioprinting. A double crosslinking model, i.e., using Ca

Indexed as

AlginatesBioprintingCalciumCell Culture TechniquesCell Line, TumorCell ProliferationComputer-Aided DesignCross-Linking ReagentsGelatinHardnessHumansHydrogelsMicroscopy, ConfocalMicroscopy, Electron, ScanningNeuroblastomaTransglutaminasesAlginatesCalciumCross-Linking ReagentsGelatinHydrogelsTransglutaminasesWateralginate/gelatin hydrogelsinterpenetrating polymer network (IPN)in vitro cell culturesSH-SY5Y cellsthree-dimensional (3D) bioprinting

Identifiers

PMID32050529
PMCPMC7036974
OpenAlexW3004796386

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.