Evidence map›Paper›PMID 32050463›Full record

ArticleNutrients2020

In Vitro Hypocholesterolemic Effect of Coffee Compounds.

Filipe Manuel Coreta-Gomes, Guido R Lopes, Cláudia P Passos, Inês M Vaz, Fernanda Machado, Carlos F G C Geraldes, Maria João Moreno, Laura Nyström, Manuel A Coimbra

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Review
  3. Water-SolubleMarine drugs · 2023
    Article
  4. Effect of Coffee on the Bioavailability of Sterols.Foods (Basel, Switzerland) · 2022
    Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Filipe Manuel Coreta-GomesLAQV-REQUIMTE, Chemistry Department, University of Aveiro, 3810-193 Aveiro, Portugal.
Guido R LopesLAQV-REQUIMTE, Chemistry Department, University of Aveiro, 3810-193 Aveiro, Portugal.
Cláudia P PassosLAQV-REQUIMTE, Chemistry Department, University of Aveiro, 3810-193 Aveiro, Portugal.
Inês M VazLAQV-REQUIMTE, Chemistry Department, University of Aveiro, 3810-193 Aveiro, Portugal.
Fernanda MachadoLAQV-REQUIMTE, Chemistry Department, University of Aveiro, 3810-193 Aveiro, Portugal.
Carlos F G C GeraldesCoimbra Chemistry Center, University of Coimbra, Rua Larga Largo D. Dinis, 3004-535 Coimbra, Portugal.
Maria João MorenoCoimbra Chemistry Center, University of Coimbra, Rua Larga Largo D. Dinis, 3004-535 Coimbra, Portugal.ORCID 0000-0003-3076-9905
Laura NyströmETH Zurich, Institute of Food, Nutrition and Health, Schmelzbergstrasse 9, CH-8092 Zurich, Switzerland.
Manuel A CoimbraLAQV-REQUIMTE, Chemistry Department, University of Aveiro, 3810-193 Aveiro, Portugal.ORCID 0000-0001-8898-6342
Rede de Química e Tecnologia · PTUniversity of Coimbra · PTETH Zurich · CH

Funding

Fundação para a Ciência e a Tecnologia 007630 UID/QUI/00062/2019Fundação para a Ciência e a Tecnologia PTDC/QUI-OUT/29373/2017
6 · The paper itself

Abstract

(1) Background: Cholesterol bioaccessibility is an indicator of cholesterol that is available for absorption and therefore can be a measure of hypocholesterolemic potential. In this work, the effect of commercial espresso coffee and coffee extracts on cholesterol solubility are studied in an in vitro model composed by glycodeoxycholic bile salt, as a measure of its bioaccessibility. (2) Methods: Polysaccharide extracts from coffees obtained with different extraction conditions were purified by selective precipitation with ethanol, and their sugars content were characterized by GC-FID. Hexane extraction allowed us to obtain the coffee lipids. Espresso coffee samples and extracts were tested regarding their concentration dependence on the solubility of labeled

Indexed as

Anticholesteremic AgentsCholesterolCoffeeIn Vitro TechniquesPlant ExtractsPolysaccharidesSolubilityAnticholesteremic AgentsCholesterolCoffeePlant ExtractsPolysaccharidesbile saltsbioaccessibilitycholesterolcoffeehypocholesterolemic effectlipidNMRpolysaccharidessequestration

Identifiers

PMID32050463
PMCPMC7071201
OpenAlexW3004836899

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.