Evidence map›Paper›PMID 32050455›Full record

ArticleLife (Basel, Switzerland)2020

Synthetic Biology for Terraformation Lessons from Mars, Earth, and the Microbiome.

Nuria Conde-Pueyo, Blai Vidiella, Josep Sardanyés, Miguel Berdugo, Fernando T Maestre, Victor De Lorenzo, Ricard Solé

Abstract read
In one paragraph

Article in Life (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Bifurcations and phase transitions in the origins of life.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2025
    Review
  6. Microbes Saving Lives and Reducing Suffering.Microbial biotechnology · 2025
    Article
  7. Open problems in synthetic multicellularity.NPJ systems biology and applications · 2024
    Article
  8. Review
  9. Review
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Ecological complexity and the biosphere: the next 30 years.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2022
    Article
  16. Environmental Galenics: large-scale fortification of extant microbiomes with engineered bioremediation agents.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2022
    Review
  17. Network-level containment of single-species bioengineering.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2022
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Nuria Conde-PueyoICREA-Complex Systems Lab, Universitat Pompeu Fabra, Plaça de la Mercè, 10, 08002 Barcelona, Spain;.
Blai VidiellaICREA-Complex Systems Lab, Universitat Pompeu Fabra, Plaça de la Mercè, 10, 08002 Barcelona, Spain;.
Josep SardanyésCentre de Recerca Matemàtica, Campus UAB Edifici C, 08193 Bellaterra, Barcelona, Spain;.
Miguel BerdugoICREA-Complex Systems Lab, Universitat Pompeu Fabra, Plaça de la Mercè, 10, 08002 Barcelona, Spain;.
Fernando T MaestreDepartamento de Ecología and Instituto Multidisciplinar para el Estudio del Medio "Ramon Margalef", Universidad de Alicante, Carr. de San Vicente del Raspeig, s/n, 03690 San Vicente del Raspeig, Alicante, Spain; (M.B.); (F.M.).
Victor De LorenzoSystems and Synthetic Biology Program, Centro Nacional de Biotecnología (CNB-CSIC), Campus de Cantoblanco, 28049 Madrid, Spain.
Ricard SoléICREA-Complex Systems Lab, Universitat Pompeu Fabra, Plaça de la Mercè, 10, 08002 Barcelona, Spain;.

Funding

H2020 Future and Emerging Technologies PR01018-EC-H2020- FET-Open MADONNAMinisterio de Ciencia, Tecnología e Innovación Productiva FIS2015-67616- P
6 · The paper itself

Abstract

What is the potential for synthetic biology as a way of engineering, on a large scale, complex ecosystems? Can it be used to change endangered ecological communities and rescue them to prevent their collapse? What are the best strategies for such ecological engineering paths to succeed? Is it possible to create stable, diverse synthetic ecosystems capable of persisting in closed environments? Can synthetic communities be created to thrive on planets different from ours? These and other questions pervade major future developments within synthetic biology. The goal of engineering ecosystems is plagued with all kinds of technological, scientific and ethic problems. In this paper, we consider the requirements for terraformation, i.e., for changing a given environment to make it hospitable to some given class of life forms. Although the standard use of this term involved strategies for planetary terraformation, it has been recently suggested that this approach could be applied to a very different context: ecological communities within our own planet. As discussed here, this includes multiple scales, from the gut microbiome to the entire biosphere.

Indexed as

drylandsevolutionhypercyclesMarsmicrobiomerestoration ecologysynthetic biologyterraformation

Identifiers

PMID32050455
PMCPMC7175242

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.