ReviewNanomaterials (Basel, Switzerland)2020
Metal-Based Nanoparticles as Antimicrobial Agents: An Overview.
Review in Nanomaterials (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 424 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
424 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Antibiotic Nanoparticles-Loaded Wound Dressings AgainstInternational journal of nanomedicine · 2024Pooled it
- Green synthesis of a manganese oxide-selenium nanocomposite using watermelon peel waste with antimicrobial and mosquitocidal activities.RSC advances · 2026Article
- Remedial applications of biosynthesized metal oxide nanoparticles against pathogenic microorganisms.Discover nano · 2026Review
- Development of Antimicrobial Coatings by Incorporating Curcumin and Silver-Based Additive into a Commercial Water-Based Paint.Biomimetics (Basel, Switzerland) · 2026Article
- Antibiotic-Free Strategies for Managing Antimicrobial-Resistant Infections.Pharmaceutics · 2026Review
- Sustainable Antimicrobial Textiles Functionalized with Gold and Silver Nanoparticles Biosynthesized UsingNanomaterials (Basel, Switzerland) · 2026Article
- Dual Anticancer and Antibacterial Applications of Active Particle Aggregates Containing Metal Phthalocyanines in Dark.International journal of molecular sciences · 2026Article
- Nanotechnology-Driven Strategies to Combat Antimicrobial Resistance in the One Health Era.Journal of clinical practice and research · 2026Review
- Applications of Bioinorganic Nano-Based Delivery Systems-Diagnostics and Therapeutics.Drug development research · 2026Review
- Nanotechnology-Enabled Strategies to Overcome Antibiotic Resistance in Respiratory Infections: Mechanisms, Platforms, and Translational Challenges.Biomedicines · 2026Review
- Antibacterial and wound healing activities of AgNPs, ZnONPs, and FeBMC research notes · 2026Article
- Engineering Alginate Membranes With Green Propolis-Coated Silver Nanoparticles for Potential Use in Wound Dressing.Chemistry & biodiversity · 2026Article
- Smart Nano-Antibiotics: AI-Guided Stimuli-Responsive Nanoplatforms for Precision Antimicrobial Therapy.Antibiotics (Basel, Switzerland) · 2026Review
- Phytochemical-mediated green synthesis, mechanistic insights integrated with biological evaluation, density functional theory calculations and molecular docking studies of copper oxide nanoparticles.Scientific reports · 2026Article
- Biosynthesis of ecofriendly antibacterial nanoparticles with healing effects in a murine diabetic skin infection model.Scientific reports · 2026Article
- Silver Nanoparticles Produced by Rooibos Kombucha Suppress Bacterial Biofilms and Improve Survival inInternational journal of molecular sciences · 2026Article
- Green Synthesis of Gold Nanoparticles with Good Photothermal Properties and Antibacterial Activity from Black Corncob Extract.Nanomaterials (Basel, Switzerland) · 2026Article
- Crosslinked-AuNPs@CD-MOF Incorporated into PLA-Zein Composite Film with Humidity-Responsive Antimicrobial Release forFoods (Basel, Switzerland) · 2026Article
- Green synthesis of silver nanoparticles withRSC advances · 2026Article
- Synthesis of 2-Aryl-4-aminoquinazolines: Design, Molecular Docking, and In Vitro Assessment of Antibacterial and Cytotoxic Potential.International journal of molecular sciences · 2026Article
364 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
15 authors.
Funding
Abstract
Metal-based nanoparticles have been extensively investigated for a set of biomedical applications. According to the World Health Organization, in addition to their reduced size and selectivity for bacteria, metal-based nanoparticles have also proved to be effective against pathogens listed as a priority. Metal-based nanoparticles are known to have non-specific bacterial toxicity mechanisms (they do not bind to a specific receptor in the bacterial cell) which not only makes the development of resistance by bacteria difficult, but also broadens the spectrum of antibacterial activity. As a result, a large majority of metal-based nanoparticles efficacy studies performed so far have shown promising results in both Gram-positive and Gram-negative bacteria. The aim of this review has been a comprehensive discussion of the state of the art on the use of the most relevant types of metal nanoparticles employed as antimicrobial agents. A special emphasis to silver nanoparticles is given, while others (e.g., gold, zinc oxide, copper, and copper oxide nanoparticles) commonly used in antibiotherapy are also reviewed. The novelty of this review relies on the comparative discussion of the different types of metal nanoparticles, their production methods, physicochemical characterization, and pharmacokinetics together with the toxicological risk encountered with the use of different types of nanoparticles as antimicrobial agents. Their added-value in the development of alternative, more effective antibiotics against multi-resistant Gram-negative bacteria has been highlighted.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.