Evidence map›Paper›PMID 32050401›Full record

ArticleThe Science of the total environment2020

Enhancing life cycle chemical exposure assessment through ontology modeling.

David E Meyer, Sidney C Bailin, Daniel Vallero, Peter P Egeghy, Shi V Liu, Elaine A Cohen Hubal

Abstract read
In one paragraph

Article in The Science of the total environment, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Exposure forecasting - ExpoCast - for data-poor chemicals in commerce and the environment.Journal of exposure science & environmental epidemiology · 2022
    Review
  6. The Human Disease Ontology 2022 update.Nucleic acids research · 2022
    Article
  7. Article
  8. Article
  9. Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

David E MeyerU.S. Environmental Protection Agency, Center for Environmental Solutions and Emergency Response, 26 West Martin Luther King Drive, Cincinnati, OH 45268, United States. Electronic address: Meyer.David@epa.gov.
Sidney C BailinKnowledge Evolution, Inc., 1748 Seaton Street NW, Washington, DC 20009, United States.
Daniel ValleroU.S. Environmental Protection Agency, Center for Computational Toxicology and Exposure, 109 TW Alexander Drive, Durham, NC 27709, United States.
Peter P EgeghyU.S. Environmental Protection Agency, Center for Computational Toxicology and Exposure, 109 TW Alexander Drive, Durham, NC 27709, United States.
Shi V LiuU.S. Environmental Protection Agency, Center for Public Health and Environmental Assessment, 109 TW Alexander Drive, Durham, NC 27709, United States.
Elaine A Cohen HubalU.S. Environmental Protection Agency, Center for Public Health and Environmental Assessment, 109 TW Alexander Drive, Durham, NC 27709, United States.

Funding

Institutional Career Development CoreKL2TR003168 · NCATS · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI MILLER, CHARLES C · 2019 to 2023
$4.9M
Intramural EPA EPA999999
6 · The paper itself

Abstract

In its 2014 report, A Framework Guide for the Selection of Chemical Alternatives, the National Academy of Sciences placed increased emphasis on comparative exposure assessment throughout the life cycle (i.e., from manufacturing to end-of-life) of a chemical. The inclusion of the full life cycle greatly increases the data demands for exposure assessments, including both the quantity and type of data. High throughput tools for exposure estimation add to this challenge by requiring rapid accessibility to data. In this work, ontology modeling was used to bridge the domains of exposure modeling and life cycle inventory modeling to facilitate data sharing and integration. The exposure ontology, ExO, is extended to describe human exposure to consumer products, while an inventory modeling ontology, LciO, is formulated to support automated data mining. The core ontology pieces are connected using a bridging ontology and discussed through a theoretical example to demonstrate how data from LCA can be leveraged to support rapid exposure modeling within a life cycle context.

Indexed as

Life Cycle StagesRisk AssessmentConsumer productsData accessibilityHuman exposure modelingLife cycle assessmentOntology modelingp-Dichlorobenzene

Identifiers

PMID32050401
PMCPMC7453614

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.