Evidence map›Paper›PMID 32049895›Full record

SynthesisPain2020

Positive affect and chronic pain: a preregistered systematic review and meta-analysis.

Anthony D Ong, Felix Thoemmes, Kaylin Ratner, Kate Ghezzi-Kopel, M Carrington Reid

Open access · greenAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Pain, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 2 pooled it
4.3field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 2 syntheses or guidelines pooled it, 59 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Trial
  5. Trial
  6. Trial
  7. Trial
  8. Trial
  9. Trial
  10. Article
  11. Article
  12. Article
  13. Sex differences in the transition to chronic pain.The Journal of clinical investigation · 2025
    Review
  14. Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Anthony D OngDepartment of Human Development, Cornell University, Ithaca, NY.
Felix ThoemmesDepartment of Human Development, Cornell University, Ithaca, NY.
Kaylin RatnerDepartment of Human Development, Cornell University, Ithaca, NY.
Kate Ghezzi-KopelAlbert R. Mann Library, Cornell University, Ithaca, NY.
M Carrington ReidDepartment of Medicine, Weill Cornell Medical College, New York City, NY, United States.
Cornell University · US

Funding

Pilot CoreP30AG022845 · NIA · WEILL MEDICAL COLL OF CORNELL UNIV · PI Manney Carrington Reid · 2003 to 2026
$15.2M
Reid Aging and Pain Research Training ProgramK24AG053462 · NIA · WEILL MEDICAL COLL OF CORNELL UNIV · PI REID, MANNEY CARRINGTON · 2016 to 2025
$1.8M
NIA NIH HHS K24 AG053462NIA NIH HHS P30 AG022845
6 · The paper itself

Abstract

Chronic noncancer pain (CNCP) is a significant health burden among adults. Standard behavioral therapies typically focus on targeting negative affect (NA) and yield only modest treatment effects. The aims of this study were to systematically review and investigate the association between positive affect (PA) and pain severity among adults with CNCP. Databases that were searched included MEDLINE (PubMed), PsycINFO, CINAHL, ProQuest Dissertations and Theses, OLASTER, Open Grey, and PsyArXiv (inception to July 23, 2019). We analyzed studies that: (1) used observational, experimental, or intervention study designs; (2) enrolled individuals with CNCP (pain ≥ 12 weeks); and (3) reported full quantitative results on outcomes. Two researchers independently screened articles, extracted data, and assessed the risk of bias. The main meta-analysis was followed by subgroup analyses. All analyses were performed using random-effects models. Formal tests for heterogeneity (Q-statistic; I) and publication bias (p-curve and p-uniform*) were performed. We meta-analyzed 29 studies with 3521 participants. Results demonstrated that PA inversely impacts pain severity in people with CNCP (r = -0.23). Subgroup analyses showed a significant effect for gender and marginally significant effects for age in studies that adjusted for NA. On average, effect sizes for observational studies were larger in studies with a higher proportion of female respondents and in studies that did not adjust for NA. Finally, larger effect sizes were found in intervention studies with older compared with younger samples.

Indexed as

Chronic PainAdultAnalgesics, OpioidFemaleHumansAnalgesics, Opioid

Identifiers

PMID32049895
PMCPMC7230030
OpenAlexW3006474210

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.