Evidence map›Paper›PMID 32049833›Full record

Trial reportMedicine2020

Effects of early virtual reality-based rehabilitation in patients with total knee arthroplasty: A randomized controlled trial.

Silvia Gianola, Elena Stucovitz, Greta Castellini, Mariangela Mascali, Francesco Vanni, Irene Tramacere, Giuseppe Banfi, Davide Tornese

Registry-linked trialAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02413996 (Effects of Virtual Reality Rehabilitation in Patients With Total Knee Arthroplasty), which is not on this map. Cited by 46 papers, 10 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed, 10 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02413996 nacompletednot on this map

Effects of Virtual Reality Rehabilitation in Patients With Total Knee Arthroplasty: A Randomised Controlled Trial

TypeinterventionalSponsorI.R.C.C.S Ospedale Galeazzi-Sant'AmbrogioRan2014 to 2018Enrolled85ConditionsTotal Knee Replacement, Virtual Reality Therapy, Osteoarthritis, Knee ArthroplastyArmsKinetec® knee continuous passive motion (CPM ), Functional activities, VRRS rehabilitation, traditional rehabilitation
3 · Its place in the literature

Who cites it

46 citing papers in PubMed, 10 syntheses or guidelines pooled it.

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  16. Digitally assistedWorld journal of clinical cases · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Silvia GianolaIRCCS Istituto Ortopedico Galeazzi, Unit of Clinical Epidemiology.
Elena StucovitzIRCCS Istituto Ortopedico Galeazzi, Motion Analysis Laboratory.
Greta CastelliniIRCCS Istituto Ortopedico Galeazzi, Unit of Clinical Epidemiology.
Mariangela MascaliIRCCS Istituto Ortopedico Galeazzi, Center for Sports Rehabilitation.
Francesco VanniIRCCS Istituto Ortopedico Galeazzi, Center for Sports Rehabilitation.
Irene TramacereDepartment of Research and Clinical Development, Scientific Directorate, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milan, Italy.
Giuseppe BanfiIRCCS Istituto Ortopedico Galeazzi, Scientific Directorate.
Davide TorneseIRCCS Istituto Ortopedico Galeazzi, Center for Sports Rehabilitation.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundVirtual reality (VR)-based rehabilitation is a promising approach for improving recovery in many conditions to optimize functional results, enhancing the clinical and social benefits of surgery.

objectiveTo assess the efficacy of an early rehabilitation performed by the VR-based rehabilitation versus the traditional rehabilitation provided by physical therapists after primary total knee arthroplasty (TKA).

methodsIn this randomized controlled clinical trial, 85 subjects met the inclusion criteria and were randomized 3 to 4 days after TKA to an inpatient VR-based rehabilitation and a traditional rehabilitation. Participants in both groups received 60 minutes/day sessions until discharge (around 10 days after surgery). The primary outcome was the pain intensity. The secondary outcomes were: the disability knee, the health related quality of life, the global perceived effect, the functional independent measure, the drugs assumption, the isometric strength of quadriceps and hamstrings, the flexion range of motion, and the ability to perform proprioception exercises. Outcomes were assessed at baseline (3-4 days after TKA) and at discharge.

resultsVR-based or traditional rehabilitation, with 13% of dropout rate, shown no statistically significant pain reduction between groups (P = .2660) as well as in all other outcomes, whereas a statistically significant improvement was present in the global proprioception (P = .0020), in favor of the VR-based rehabilitation group.

conclusionsVR-based rehabilitation is not superior to traditional rehabilitation in terms of pain relief, drugs assumptions and other functional outcomes but seems to improve the global proprioception for patients received TKA. LEVEL OF EVIDENCE: Therapy, level 1b. CONSORT-compliant.

trial registrationhttp://www.clinicaltrials.gov, ClinicalTrials.gov, NCT02413996.

Indexed as

AgedArthroplasty, Replacement, KneeFemaleHumansMaleMiddle AgedPostoperative PainQuality of LifeTreatment OutcomeVirtual Reality Exposure Therapy

Identifiers

PMID32049833
PMCPMC7035049

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.