ArticleInvestigative radiology2020
A Universal Protocol for Abdominal CT Examinations Performed on a Photon-Counting Detector CT System: A Feasibility Study.
Article in Investigative radiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed.
- A Practical Rule-of-Thumb to Adapt Contrast Media Dose in Photon-counting Detector CT: The 10-to-5 Rule.Investigative radiology · 2026Article
- Photon-counting CT for paraspinal muscle fat quantification compared with MRI proton density fat fraction.BMC medical imaging · 2026Article
- Contrast media and radiation dose optimization with task-based automatic keV selection: a proof-of-concept study with photon-counting detector CT.European radiology · 2025Article
- Photon-counting detector computed tomography: iodine density versus virtual monoenergetic imaging of pancreatic ductal adenocarcinoma.Abdominal radiology (New York) · 2025Article
- Overcoming the thermal limits of photon counting CT resolution using focal spot multiplexing: A feasibility study.Medical physics · 2025Article
- Low-contrast detectability of photon-counting-detector CT at different scan modes and image types in comparison with energy-integrating-detector CT.Journal of medical imaging (Bellingham, Wash.) · 2024Article
- Standardizing technical parameters and terms for abdominopelvic photon-counting CT: laying the groundwork for innovation and evidence sharing.Abdominal radiology (New York) · 2024Review
- Task-based automatic keV selection: leveraging routine virtual monoenergetic imaging for dose reduction on clinical photon-counting detector CTPhysics in medicine and biology · 2024Article
- [A comprehensive review on photon-counting computed tomography: Principles, technical hurdles and analysis of clinical applications].Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi · 2023Review
- Clinical applications of photon counting detector CT.European radiology · 2023Review
- Quantum iterative reconstruction on a photon-counting detector CT improves the quality of hepatocellular carcinoma imaging.Cancer imaging : the official publication of the International Cancer Imaging Society · 2023Article
- An introduction to photon-counting detector CT (PCD CT) for radiologists.Japanese journal of radiology · 2023Review
- Evaluation of Low-contrast Detectability of Photon-Counting-Detector CT Using Channelized Hotelling Observer and an ACR Accreditation Phantom.Proceedings of SPIE--the International Society for Optical Engineering · 2023Article
- Quantum Iterative Reconstruction for Low-Dose Ultra-High-Resolution Photon-Counting Detector CT of the Lung.Diagnostics (Basel, Switzerland) · 2022Article
- Dual-Contrast Biphasic Liver Imaging With Iodine and Gadolinium Using Photon-Counting Detector Computed Tomography: An Exploratory Animal Study.Investigative radiology · 2022Article
- Virtual monoenergetic images from dual-energy CT: systematic assessment of task-based image quality performance.Quantitative imaging in medicine and surgery · 2022Article
- Simultaneous Dual-Contrast Imaging of Small Bowel With Iodine and Bismuth Using Photon-Counting-Detector Computed Tomography: A Feasibility Animal Study.Investigative radiology · 2020Article
- Optimal Virtual Monoenergetic Photon Energy (keV) for Photon-Counting-Detector Computed Tomography Angiography.Journal of computer assisted tomographyArticle
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
objectiveThe aims of this study were to investigate the feasibility of using a universal abdominal acquisition protocol on a photon-counting detector computed tomography (PCD-CT) system and to compare its performance to that of single-energy (SE) and dual-energy (DE) CT using energy-integrating detectors (EIDs).
methodsIodine inserts of various concentrations and sizes were embedded into different sizes of adult abdominal phantoms. Phantoms were scanned on a research PCD-CT and a clinical EID-CT with SE and DE modes. Virtual monoenergetic images (VMIs) were generated from PCD-CT and DE mode of EID-CT. For each image type and phantom size, contrast-to-noise ratio (CNR) was measured for each iodine insert and the area under the receiver operating characteristic curve (AUC) for iodine detectability was calculated using a channelized Hotelling observer. The optimal energy (in kiloelectrovolt) of VMIs was determined separately as the one with highest CNR and the one with the highest AUC. The PCD-CT VMIs at the optimal energy were then compared with DE VMIs and SE images in terms of CNR and AUC.
resultsVirtual monoenergetic image at 50 keV had both the highest CNR and highest AUC for PCD-CT and DECT. For 1.0 mg I/mL iodine and 35 cm phantom, the CNRs of 50 keV VMIs from PCD-CT (2.01 ± 0.67) and DE (1.96 ± 0.52) were significantly higher (P < 0.001, Wilcoxon signed-rank test) than SE images (1.11 ± 0.35). The AUC of PCD-CT (0.98 ± 0.01) was comparable to SE (0.98 ± 0.01), and both were slightly lower than DE (0.99 ± 0.01, P < 0.01, Wilcoxon signed-rank test). A similar trend was observed for other phantom sizes and iodine concentrations.
conclusionsVirtual monoenergetic images at a fixed energy from a universal acquisition protocol on PCD-CT demonstrated higher iodine CNR and comparable iodine detectability than SECT images, and similar performance compared with DE VMIs.
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