Evidence map›Paper›PMID 32049594›Full record

ArticleMolecular biology of the cell2020

Feedback regulation of BMP signaling by

Uday Madaan, Lionel Faure, Albar Chowdhury, Shahrear Ahmed, Emma J Ciccarelli, Tina L Gumienny, Cathy Savage-Dunn

Open access · bronzeAbstract readVideo-Audio Media
In one paragraph

Article in Molecular biology of the cell, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.2field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Review
  8. Article
  9. Review
  10. Article
  11. The CHARGE syndrome ortholog CHD-7 regulates TGF-β pathways inProceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  12. Reciprocal interactions between transforming growth factor beta signaling and collagens: Insights from Caenorhabditis elegans.Developmental dynamics : an official publication of the American Association of Anatomists · 2022
    Article
  13. Journal of developmental biology · 2020
    Review
  14. Review
  15. Article
  16. Loss ofmicroPublication biology · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Uday MadaanDepartment of Biology, Queens College, City University of New York, Flushing, NY 11367.
Lionel FaureDepartment of Biology, Texas Woman's University, Denton, TX 76204.
Albar ChowdhuryDepartment of Biology, Queens College, City University of New York, Flushing, NY 11367.
Shahrear AhmedDepartment of Biology, Queens College, City University of New York, Flushing, NY 11367.
Emma J CiccarelliDepartment of Biology, Queens College, City University of New York, Flushing, NY 11367.
Tina L GumiennyDepartment of Biology, Texas Woman's University, Denton, TX 76204.
Cathy Savage-DunnDepartment of Biology, Queens College, City University of New York, Flushing, NY 11367.
Queens College, CUNY · USTexas Woman's University · US

Funding

Enhancing and expanding the CGC Strain CollectionP40OD010440 · OD · UNIVERSITY OF MINNESOTA · PI Ann E. Rougvie · 2012 to 2026
$7.5M
Molecular Mechanisms Regulating Intercellular Transit of TGF-betaR01GM097591 · NIGMS · TEXAS WOMAN'S UNIVERSITY · PI GUMIENNY, TINA L · 2011 to 2015
$1.0M
Regulation of Metabolism by C. Elegans DBL-1/BMP SignalingR15GM112147 · NIGMS · QUEENS COLLEGE · PI SAVAGE-DUNN, CATHY · 2015 to 2019
$832k
NIGMS NIH HHS R01 GM097591NIGMS NIH HHS R15 GM112147NIH HHS P40 OD010440
6 · The paper itself

Abstract

Cellular responsiveness to environment, including changes in extracellular matrix (ECM), is critical for normal processes such as development and wound healing, but can go awry, as in oncogenesis and fibrosis. One type of molecular pathway contributing to this responsiveness is the BMP signaling pathway. Owing to their broad and potent functions, BMPs and their pathways are regulated at multiple levels. In

Indexed as

AnimalsAnimal StructuresCaenorhabditis elegansCaenorhabditis elegans ProteinsCollagenFeedback, PhysiologicalGenes, ReporterNeuropeptidesRNA InterferenceSignal TransductionSmad ProteinsTranscription, GeneticTransforming Growth Factor betaCaenorhabditis elegans ProteinsCollagenDbl-1 protein, C elegansNeuropeptidesSmad ProteinsTransforming Growth Factor beta

Identifiers

PMID32049594
PMCPMC7185965
OpenAlexW3013436510

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.