Evidence map›Paper›PMID 32049186›Full record

ArticleActa cirurgica brasileira2020

Comparative study on the efficacy of non-steroidal, steroid and non-use of anti-inflammatory in the treatment of acute epidemic conjunctivitis.

Luiz Alfredo Santiago, Jussara Matyelle Rodrigues da Silva, Orleâncio Gomes Ripardo de Azevedo, Paulo Roberto Leitão de Vasconcelos

Open access · goldAbstract readComparative StudyEvaluation Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Acta cirurgica brasileira, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 5 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Artificial Tears: A Systematic Review.Clinical optometry · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Luiz Alfredo SantiagoMaster in Surgery, and Physician, Hospital de Olhos Leiria de Andrade, Fortaleza-CE, Brazil. Acquisition of data, technical procedures, manuscript writing.ORCID http://orcid.org/0000-0001-9412-4706
Jussara Matyelle Rodrigues da SilvaFellow Master degree, Pharmacology Department, Universidade Federal do Ceará (UFC), Fortaleza-CE, Brazil. Statistical analysis, analysis and interpretation of data, technical procedures.ORCID http://orcid.org/0000-0002-8210-9055
Orleâncio Gomes Ripardo de AzevedoPos Doc, Postgraduate Program, Department of Surgery, UFC, Fortaleza-CE, Brazil. Manuscript preparation and writing, critical revision.ORCID http://orcid.org/0000-0003-4530-0093
Paulo Roberto Leitão de VasconcelosPhD, Full Professor, Coordinator, Postgraduate Program in Surgery, Department of Surgery, UFC, Fortaleza-CE, Brazil. Intellectual and scientific content of the study, critical revision, final approval.
Hospital Geral de Fortaleza · BRInstituto de Olhos de Goiânia · BRUniversidade Federal do Ceará · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo evaluate the effects of prednisolone against sodium diclofenac both with ciprofloxacin compared to artificial tears on the symptoms and signs of acute viral conjunctivitis.

methodsStudy included 37 patients diagnosed with acute conjunctivitis and distributed by three groups: A (1% prednisolone acetate + ciprofloxacin (0.3%); B (Sodium diclofenac (0.1%) + ciprofloxacin (0.3%) and C (artificial tears + ciprofloxacin (0.3%). Patients received medication 6/6 hours daily. Signs and symptoms (e.g. lacrimation, burning, photophobia, etc.) were scored at baseline and on the first, third, fifth and seventh days and in the end of treatment using a standardized questionnaire and slit lamp anterior segment examination.

resultsAll three groups demonstrated an improvement in the signs and symptoms of conjunctivitis in their follow-up visits. There was no significant difference in symptom and sign scores between Group A and B and B and C in the study visits ( p >0.05). However, the comparison between groups A and C showed a clinical trend (p=0.05) on third evaluation suggesting better clinical action using the corticosteroids.

conclusionThe prednisolone acetate was not superior to the use of sodium diclofenac or artificial tears in relieving the signs and symptoms of viral conjunctivitis.

Indexed as

Acute DiseaseAdolescentAdrenal Cortex HormonesAdultAgedAnalysis of VarianceAnti-Inflammatory Agents, Non-SteroidalCiprofloxacinConjunctivitis, ViralDiclofenacFemaleHumansInterferon-gammaInterleukinsLubricant Eye DropsMaleAdrenal Cortex HormonesAnti-Inflammatory Agents, Non-SteroidalCiprofloxacinDiclofenacInterferon-gammaInterleukinsLubricant Eye DropsNitric Oxide SynthaseOphthalmic SolutionsPrednisoloneprednisolone acetateTumor Necrosis Factor-alpha

Identifiers

PMID32049186
PMCPMC7006370
OpenAlexW3004973381

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.