ArticleJournal of biomedical materials research. Part B, Applied biomaterials2020
Biodegradable magnesium alloy (WE43) in bone-fixation plate and screw.
Article in Journal of biomedical materials research. Part B, Applied biomaterials, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
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Who cites it
27 citing papers in PubMed, 83 citations in OpenAlex.
- Low addition of Er and Zn into biomedical magnesium with enhanced integrated properties for orthopedic applications:Bioactive materials · 2026Article
- Control of Corrosion Resistance and Osteoclastic Resorbability of Bioresorbable Carbonate Apatite Coating for Biodegradable Mg Alloys through Carbonate Content.ACS biomaterials science & engineering · 2026Article
- Synergistic effects of biodegradable magnesium alloy and erythromycin on osteogenic activity.Journal of dental sciences · 2026Article
- Effect of powder particle concentration, pulse duration, and pulse current on machined surface characterization produced via EDM of biocompatible WE-43Mg alloy.Scientific reports · 2025Article
- Degradation of WE43 Magnesium Alloy in Vivo and Its Degradation Products on Macrophages.ACS omega · 2025Article
- Article
- Biomechanical stability of magnesium plate and screw fixation systems in LeFort I osteotomy: a three-dimensional finite element analysis.Maxillofacial plastic and reconstructive surgery · 2024Article
- Safety and efficacy of Mg-Dy membrane with poly-L-lactic acid coating for guided bone regeneration.Scientific reports · 2024Article
- Gingivo-Periosteal Expansion of Edentulous Jaw Crest with An Osmotic Self-Inflatable Expander: A Preclinical in Vivo Study.The Journal of craniofacial surgery · 2024Article
- Duplex Fluorinated and Atomic Layer Deposition-Derived ZrOMaterials (Basel, Switzerland) · 2024Article
- Resorbable Patient-Specific Implants of Molybdenum for Pediatric Craniofacial Surgery-Proof of Concept in an In Vivo Pilot Study.Journal of functional biomaterials · 2024Article
- Experimental study on determining the degree of bone healing by wall thickness ratio analysis.Journal of orthopaedic surgery and research · 2024Article
- Magnesium implant degradation provides immunomodulatory and proangiogenic effects and attenuates peri-implant fibrosis in soft tissues.Bioactive materials · 2023Article
- Effect of the Combination of Torsional and Tensile Stress on Corrosion Behaviors of Biodegradable WE43 Alloy in Simulated Body Fluid.Journal of functional biomaterials · 2023Article
- Magnesium-based alloys with adapted interfaces for bone implants and tissue engineering.Regenerative biomaterials · 2023Review
- Biomechanical Comparison of WE43-Based Magnesium vs. Titanium Miniplates in a Mandible Fracture Model in Sheep.Materials (Basel, Switzerland) · 2022Article
- Applications of Biodegradable Magnesium-Based Materials in Reconstructive Oral and Maxillofacial Surgery: A Review.Molecules (Basel, Switzerland) · 2022Review
- Biologically modified implantation as therapeutic bioabsorbable materials for bone defect repair.Regenerative therapy · 2022Review
- Quality of reporting and adherence to the ARRIVE guidelines 2.0 for preclinical degradable metal research in animal models of bone defect and fracture: a systematic review.Regenerative biomaterials · 2022Review
- Research status of biodegradable metals designed for oral and maxillofacial applications: A review.Bioactive materials · 2021Review
Corrections and comments
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Authors and funding
6 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The purpose of the present study was to evaluate the mechanical strength and the absorption rate of WE43 material and to develop an absorbable metallic plate and screw for craniofacial application. The extruded WE43 plate and screw were evaluated using a LeFort I osteotomy canine model of 10 beagle dogs. Animals were divided into two groups: five dogs in the experimental group and five dogs in the control group. μCT was acquired at 4, 12, and 24 weeks. At 24 weeks after the operation, all animals were sacrificed, and histologic evaluation was performed. Swelling and gas formation were observed in three dogs in the experimental groups at 8 weeks. From 12 weeks, infraorbital fistula and inflammation were observed in three dogs in the experimental group, which gradually decreased and disappeared at 24 weeks. Other two dogs showed less gas formation at 12 weeks. The plates were completely absorbed, and gas formation was not observed at 24 weeks in these two dogs. New bone was well formed around the plates and screws in both groups. Histologic examination showed no specific differences between two groups. The mechanical strength of extruded WE43 was sufficient for mid-facial application. Plates and screws made with appropriately treated WE43 have the potential to be useful clinically.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.