Evidence map›Paper›PMID 32048632›Full record

ArticleMedical science monitor : international medical journal of experimental and clinical research2020

Downregulation of MiR-218-5p Protects Against Oxygen-Glucose Deprivation/Reperfusion-Induced Injuries of PC12 Cells via Upregulating N-myc Downstream Regulated Gene 4 (NDRG4).

Huiying Zhu, Xiaojing Wang, Shaoyuan Chen

Open access · hybridAbstract read
In one paragraph

Article in Medical science monitor : international medical journal of experimental and clinical research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 22 citations in OpenAlex.

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  11. MicroRNA-218 aggravates HExperimental and therapeutic medicine · 2021
    Article
  12. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Huiying ZhuDepartment of Neurology, Wuhan First Hospital, Wuhan, Hubei, China (mainland).
Xiaojing WangDepartment of Neurology, Hospital, Baicheng, Jilin, China (mainland).
Shaoyuan ChenDepartment of Neurology, Hospital, Baicheng, Jilin, China (mainland).
BaiCheng Normal University · CNWuhan Third Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

<strong>BACKGROUND</strong> Cerebral ischemia is a major player of acute ischemic stroke (AIS) and mainly caused by blood vessels obstruction-induced reduced blood flow. Furthermore, miR-218-5p level was elevated in patients with AIS compared with controls. The present study investigated the biochemical mechanisms underlying the role of miR-218-5p in AIS

Indexed as

AnimalsApoptosisBiomarkersCulture MediaDown-RegulationGlucoseHumansIschemic StrokeMicroRNAsMuscle ProteinsNerve Tissue ProteinsOxidative StressOxygenPC12 CellsRatsReperfusion InjuryBiomarkersCulture MediaGlucoseMicroRNAsMIRN218 microRNA, ratMuscle ProteinsNdrg4 protein, ratNerve Tissue ProteinsOxygen

Identifiers

PMID32048632
PMCPMC7009718
OpenAlexW3000700435

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.