Evidence map›Paper›PMID 32048604›Full record

ArticleJournal of studies on alcohol and drugs2020

Alcohol Dependence and Reproductive Onset in Women, Updated: Analyses of Research and State-Level Administrative Data.

Mary Waldron, Kathleen K Bucholz, Pamela A F Madden, Andrew C Heath

Open access · greenAbstract readTwin Study
In one paragraph

Article in Journal of studies on alcohol and drugs, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.7field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Mary WaldronDepartment of Counseling and Educational Psychology, School of Education, Indiana University, Bloomington, Indiana.
Kathleen K BucholzMidwest Alcoholism Research Center, Department of Psychiatry, Washington University School of Medicine, St. Louis, Missouri.
Pamela A F MaddenMidwest Alcoholism Research Center, Department of Psychiatry, Washington University School of Medicine, St. Louis, Missouri.
Andrew C HeathMidwest Alcoholism Research Center, Department of Psychiatry, Washington University School of Medicine, St. Louis, Missouri.
Washington University in St. Louis · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe present study updates prior research, incorporating state-level administrative data to examine associations between self-reported history of alcohol dependence and birth record-derived reproductive onset, the latter assessed through peak childbearing years.

methodParticipants included 542 African ancestry (AA) and 2,928 European or other ancestry (EA) female twins ascertained through Missouri birth records and recruited as part of a birth cohort study of like-sex female pairs born between 1975 and 1985. Analyses were limited to twins for whom residence in Missouri when of reproductive age could be documented, including twins who left Missouri but later returned. Cox proportional hazards regression models were estimated predicting age at first childbirth from history of alcohol dependence, separately for AA and EA twins, without and with adjustment for sociodemographic characteristics, comorbid psychopathology and other substance involvement, overweight/obesity status, and family-of-origin and childhood risk factors.

resultsAmong EA twins, alcohol dependence predicted both early and delayed childbearing; in adjusted models, alcohol dependence was associated with overall delayed childbearing. Associations between alcohol dependence and reproductive onset were nonsignificant among AA twins.

conclusionsFindings for EA twins are consistent with the broader literature indicating increased risk of teen motherhood associated with early-onset and problem drinking, but suggest that this may be explained by other correlated risk factors. The more robust finding, confirming relatively recent research, is of delayed childbearing associated with alcohol dependence.

Indexed as

Maternal AgeAdultAlcoholismBlack or African AmericanBlack PeopleCohort StudiesFemaleHumansMissouriRisk FactorsSelf ReportTwinsWhite PeopleYoung Adult

Identifiers

PMID32048604
PMCPMC7024812
OpenAlexW3006282934

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.