Evidence map›Paper›PMID 32048573›Full record

ArticleNeurological research2020

Use of high-sensitivity digital ELISA improves the diagnostic performance of circulating brain-specific proteins for detection of traumatic brain injury during triage.

Grant C O'Connell, Megan L Alder, Christine G Smothers, Carolyn H Still, Allison R Webel, Shirley M Moore

Open access · greenAbstract read
In one paragraph

Article in Neurological research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
3.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it, 33 citations in OpenAlex.

  1. Pooled it
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  10. CCN proteins: opportunities for clinical studies-a personal perspective.Journal of cell communication and signaling · 2023
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Grant C O'ConnellFrances Payne Bolton School of Nursing, Case Western Reserve University, Cleveland, OH, USA.ORCID https://orcid.org/0000-0002-2642-6670
Megan L AlderFrances Payne Bolton School of Nursing, Case Western Reserve University, Cleveland, OH, USA.ORCID https://orcid.org/0000-0002-7817-3476
Christine G SmothersFrances Payne Bolton School of Nursing, Case Western Reserve University, Cleveland, OH, USA.
Carolyn H StillFrances Payne Bolton School of Nursing, Case Western Reserve University, Cleveland, OH, USA.
Allison R WebelFrances Payne Bolton School of Nursing, Case Western Reserve University, Cleveland, OH, USA.
Shirley M MooreFrances Payne Bolton School of Nursing, Case Western Reserve University, Cleveland, OH, USA.
Case Western Reserve University · US

Funding

SMART Center II Brain Behavior Connections in Self Management ScienceP30NR015326 · NINR · CASE WESTERN RESERVE UNIVERSITY · PI MOORE, SHIRLEY M · 2014 to 2018
$2.8M
NINR NIH HHS P30 NR015326
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AdultAgedBiomarkersBrainBrain Injuries, TraumaticDigital TechnologyEnzyme-Linked Immunosorbent AssayFemaleHumansMaleMiddle AgedNeurofilament ProteinsReproducibility of Resultstau ProteinsTriageBiomarkersMAPT protein, humanneurofilament protein LNeurofilament Proteinstau Proteinsbiomarkersconcussionmolecular diagnosticsSiMoASingle molecule arraytriage

Identifiers

PMID32048573
PMCPMC7192520
OpenAlexW3006534520

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.