Evidence map›Paper›PMID 32048531›Full record

ArticleJournal of enzyme inhibition and medicinal chemistry2020

Discovery of small molecule inhibitors of

Fernanda A H Batista, Sérgio L Ramos, Giusy Tassone, Andrei Leitão, Carlos A Montanari, Maurizio Botta, Mattia Mori, Júlio C Borges

Open access · goldAbstract read
In one paragraph

Article in Journal of enzyme inhibition and medicinal chemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Review
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  7. Molecular Docking and Molecular Dynamics Simulations in Related toTropical medicine and infectious disease · 2023
    Review
  8. Review
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  11. Review
  12. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 3 countries.

Fernanda A H BatistaSão Carlos Institute of Chemistry (IQSC), University of São Paulo (USP), São Carlos, Brazil.
Sérgio L RamosSão Carlos Institute of Chemistry (IQSC), University of São Paulo (USP), São Carlos, Brazil.
Giusy TassoneDepartment of Biotechnology, Chemistry and Pharmacy - Department of Excellence 2018-2022, University of Siena, Siena, Italy.
Andrei LeitãoMedicinal Chemistry Group (NEQUIMED), IQSC-USP, University of São Paulo, São Carlos, Brazil.
Carlos A MontanariMedicinal Chemistry Group (NEQUIMED), IQSC-USP, University of São Paulo, São Carlos, Brazil.
Maurizio BottaDepartment of Biotechnology, Chemistry and Pharmacy - Department of Excellence 2018-2022, University of Siena, Siena, Italy.
Mattia MoriDepartment of Biotechnology, Chemistry and Pharmacy - Department of Excellence 2018-2022, University of Siena, Siena, Italy.
Júlio C BorgesSão Carlos Institute of Chemistry (IQSC), University of São Paulo (USP), São Carlos, Brazil.
Universidade de São Paulo · BRUniversity of Siena · ITSiena Biotech (Italy) · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Leishmaniasis is a neglected disease caused by the protozoa

Indexed as

Adenosine TriphosphatasesAntiprotozoal AgentsDose-Response Relationship, DrugDrug DiscoveryEnzyme InhibitorsHSP90 Heat-Shock ProteinsLeishmania braziliensisModels, MolecularMolecular ChaperonesMolecular StructureParasitic Sensitivity TestsSmall Molecule LibrariesStructure-Activity RelationshipAdenosine TriphosphatasesAntiprotozoal AgentsEnzyme InhibitorsHSP90 Heat-Shock ProteinsMolecular ChaperonesSmall Molecule LibrariesfluorescenceHsp90inhibitorsleishmaniasismolecular modelling

Identifiers

PMID32048531
PMCPMC7034072
OpenAlexW3006621664

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.