Evidence map›Paper›PMID 32048078›Full record

ArticleAIDS and behavior2020

Understanding PrEP Persistence: Provider and Patient Perspectives.

Nicole D Laborde, Patrick M Kinley, Matthew Spinelli, Eric Vittinghoff, Ryan Whitacre, Hyman M Scott, Susan P Buchbinder

Abstract read
In one paragraph

Article in AIDS and behavior, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
55citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

55 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Nicole D LabordeIndependent Researcher, San Rafael, USA. nicole@nicolelaborde.com.ORCID http://orcid.org/0000-0002-7273-2476
Patrick M KinleyDisease Prevention and Control, San Francisco Department of Public Health, San Francisco, CA, USA.
Matthew SpinelliDivision of HIV, ID, and Global Medicine, University of California, San Francisco, CA, USA.
Eric VittinghoffDepartment of Epidemiology and Biostatistics, University of California, San Francisco, CA, USA.
Ryan WhitacreDepartment of Anthropology and Sociology, Graduate Institute of International and Development Studies, Geneva, Switzerland.
Hyman M ScottDivision of HIV, ID, and Global Medicine, University of California, San Francisco, CA, USA.
Susan P BuchbinderDepartment of Epidemiology and Biostatistics, University of California, San Francisco, CA, USA.

Funding

San Francisco Vaccine and Prevention UnitUM1AI069496 · NIAID · PUBLIC HEALTH FOUNDATION ENTERPRISES · PI Susan Buchbinder, Diane V Havlir · 2012 to 2026
$30.5M
Training in HIV Translational ResearchT32AI060530 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Diane V Havlir · 2005 to 2026
$6.4M
DOT Diary (D2): Developing a mobile app with combined automated DOT and daily sexual diary for monitoring and improving PrEP adherenceR01MH109320 · NIMH · PUBLIC HEALTH FOUNDATION ENTERPRISES · PI BUCHBINDER, SUSAN · 2015 to 2018
$3.9M
PrEP Point-of-Care Brief-Intervention for Adherence among Young Men Who Have Sex with Men (PrEP2-BAY Study)K23MH122286 · NIMH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI SPINELLI, MATTHEW A. · 2020 to 2024
$1.0M
Foundation for the National Institutes of Health R01AI104309NIAID NIH HHS T32 AI060530NIAID NIH HHS UM1 AI069496NIMH NIH HHS K23 MH122286NIMH NIH HHS R01 MH109320
6 · The paper itself

Abstract

PrEP persistence, or PrEP use over time, has been shown to be short, with most PrEP users stopping within 6-12 months. Furthermore, those most vulnerable to HIV often use PrEP for shorter periods. This qualitative study explores patient, provider, and contextual factors that influence PrEP persistence. In interviews with 25 PrEP users and 18 PrEP providers in San Francisco's safety net clinics, we analyze the perceived benefits and difficulties of taking PrEP, including structural barriers. We identify different steps in receipt of PrEP care (clinic visits and lab tests, pharmacy interactions, and medication adherence), and describe barriers and facilitators for providers and patients at each step. Our findings suggest that drop-in visits, streamlined testing, standing orders for labs, and 90-day PrEP prescriptions are highly desirable for many PrEP users. Also important are the proactive provision of adherence support and counseling, and referrals for housing, substance use, and mental health services.

Indexed as

Medication AdherenceAdultAnti-HIV AgentsHealth PersonnelHIV InfectionsHumansInsurance CoverageInterviews as TopicMaleMiddle AgedPre-Exposure ProphylaxisQualitative ResearchReferral and ConsultationSafety-net ProvidersSan FranciscoAnti-HIV AgentsHIV PreventionPersistencePrEP

Identifiers

PMID32048078
PMCPMC8054778

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.