Evidence map›Paper›PMID 32048019›Full record

SynthesisSurgical endoscopy2020

EUS-guided versus endoscopic transpapillary gallbladder drainage in high-risk surgical patients with acute cholecystitis: a systematic review and meta-analysis.

Rajesh Krishnamoorthi, Mahendran Jayaraj, Viveksandeep Thoguluva Chandrasekar, Dhruv Singh, Joanna Law, Michael Larsen, Andrew Ross, Richard Kozarek, Shayan Irani

Abstract readMeta-AnalysisSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Surgical endoscopy, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed, 1 pooled it
6.8field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 1 synthesis or guideline pooled it, 85 citations in OpenAlex.

  1. Guideline
  2. Review
  3. Toward Tailored EUS-Guided Gallbladder Drainage in the Era of Lumen-Apposing Metal Stent.Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society · 2026
    Article
  4. Article
  5. Review
  6. Review
  7. Article
  8. Article
  9. Review
  10. Review
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. Endoscopic ultrasound in the management of acute cholecystitis: Practical review.Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Rajesh KrishnamoorthiDigestive Diseases Institute, Virginia Mason Medical Center, Seattle, WA, USA. Rajesh.Krishnamoorthi@virginiamason.org.
Mahendran JayarajUniversity of Nevada Las Vegas School of Medicine, Las Vegas, NV, USA.
Viveksandeep Thoguluva ChandrasekarUniversity of Kansas Medical Center, Kansas City, KS, USA.
Dhruv SinghGastroenterology and Hepatology, Mayo Clinic, Rochester, MN, USA.
Joanna LawDigestive Diseases Institute, Virginia Mason Medical Center, Seattle, WA, USA.
Michael LarsenDigestive Diseases Institute, Virginia Mason Medical Center, Seattle, WA, USA.
Andrew RossDigestive Diseases Institute, Virginia Mason Medical Center, Seattle, WA, USA.
Richard KozarekDigestive Diseases Institute, Virginia Mason Medical Center, Seattle, WA, USA.
Shayan IraniDigestive Diseases Institute, Virginia Mason Medical Center, Seattle, WA, USA.
Virginia Mason Medical Center · USMayo Clinic in Arizona · USUniversity of Kansas Medical Center · USUniversity of Nevada, Las Vegas · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn patients with acute cholecystitis who are deemed high risk for cholecystectomy, percutaneous cholecystostomy (PC) was historically performed for gallbladder drainage (GBD). There are several limitations associated with PC. Endoscopic GBD [Endoscopic transpapillary GBD (ET-GBD) and EUS-guided GBD (EUS-GBD)] is an alternative to PC. We performed a systematic review and meta-analysis to compare the effectiveness and safety of EUS-GBD versus ET-GBD.

methodsWe performed a systematic search of multiple databases through May 2019 to identify studies that compared outcomes of EUS-GBD versus ET-GBD in the management of acute cholecystitis in high-risk surgical patients. Pooled odds ratios (OR) of technical success, clinical success and adverse events between EUS-GBD and ET-GBD groups were calculated.

resultsFive studies with a total of 857 patients (EUS-GBD vs ET-GBD: 259 vs 598 patients) were included in the analysis. EUS-GBD was associated with higher technical [pooled OR 5.22 (95% CI 2.03-13.44; p = 0.0006; I

conclusionEUS-GBD has higher rate of technical and clinical success compared to ET-GBD. While the rates of overall adverse events are statistically similar, EUS-GBD has lower rate of recurrent cholecystitis. Hence, EUS-GBD is preferable to ET-GBD for endoscopic management of acute cholecystitis in select high-risk surgical patients.

Indexed as

AgedCholecystitisCholecystitis, AcuteEndoscopyFemaleGallbladderHumansMaleRetrospective StudiesAcute cholecystitisCholecystoduodenostomyCholecystogastrostomyEndoscopic transpapillaryEndoscopic ultrasoundGallbladder drainageHigh-risk surgical patients

Identifiers

PMID32048019
OpenAlexW3006665242

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.