Evidence map›Paper›PMID 32047972›Full record

ArticleSocial psychiatry and psychiatric epidemiology2020

Network structure of depression symptomology in participants with and without depressive disorder: the population-based Health 2000-2011 study.

Christian Hakulinen, Eiko I Fried, Laura Pulkki-Råback, Marianna Virtanen, Jaana Suvisaari, Marko Elovainio

Abstract read
In one paragraph

Article in Social psychiatry and psychiatric epidemiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Trial
  2. Relations among daily symptoms of depression.British journal of psychology (London, England : 1953) · 2026
    Article
  3. Article
  4. Article
  5. Clustering and drivers of symptoms observed at week six after antidepressant treatment in depressed outpatients.European psychiatry : the journal of the Association of European Psychiatrists · 2025
    Article
  6. Relations among symptoms of depression over time in at-risk youth.Journal of psychopathology and clinical science · 2023
    Article
  7. [Effect of electroconvulsive therapy on brain functional network in major depressive disorder].Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi · 2023
    Article
  8. Network and Exploratory Factorial Analysis of the Depression Clinical Evaluation Test.International journal of environmental research and public health · 2022
    Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

6 authors.

Christian HakulinenDepartment of Psychology and Logopedics, Faculty of Medicine, University of Helsinki, P.O. Box 9, 00014, Helsinki, Finland. christian.hakulinen@helsinki.fi.ORCID http://orcid.org/0000-0001-8629-9960
Eiko I FriedDepartment of Clinical Psychology, Leiden University, Leiden, The Netherlands.
Laura Pulkki-RåbackDepartment of Psychology and Logopedics, Faculty of Medicine, University of Helsinki, P.O. Box 9, 00014, Helsinki, Finland.
Marianna VirtanenSchool of Educational Sciences and Psychology, University of Eastern Finland, Joensuu, Finland.
Jaana SuvisaariThe Finnish Institute for Health and Welfare, Helsinki, Finland.
Marko ElovainioDepartment of Psychology and Logopedics, Faculty of Medicine, University of Helsinki, P.O. Box 9, 00014, Helsinki, Finland. marko.elovainio@helsinki.fi.

Funding

Kulttuurin ja Yhteiskunnan Tutkimuksen Toimikunta 310591
6 · The paper itself

Abstract

purposePutative causal relations among depressive symptoms in forms of network structures have been of recent interest, with prior studies suggesting that high connectivity of the symptom network may drive the disease process. We examined in detail the network structure of depressive symptoms among participants with and without depressive disorders (DD; consisting of major depressive disorder (MDD) and dysthymia) at two time points.

methodsParticipants were from the nationally representative Health 2000 and Health 2011 surveys. In 2000 and 2011, there were 5998 healthy participants (DD-) and 595 participants with DD diagnosis (DD+). Depressive symptoms were measured using the 13-item version of the Beck Depression Inventory (BDI). Fused Graphical Lasso was used to estimate network structures, and mixed graphical models were used to assess network connectivity and symptom centrality. Network community structure was examined using the walktrap-algorithm and minimum spanning trees (MST). Symptom centrality was evaluated with expected influence and participation coefficients.

resultsOverall connectivity did not differ between networks from participants with and without DD, but more simple community structure was observed among those with DD compared to those without DD. Exploratory analyses revealed small differences between the samples in the order of one centrality estimate participation coefficient.

conclusionsCommunity structure, but not overall connectivity of the symptom network, may be different for people with DD compared to people without DD. This difference may be of importance when estimating the overall connectivity differences between groups with and without mental disorders.

Indexed as

Major Depressive DisorderDepressionDysthymic DisorderHealth SurveysHumansPsychiatric Status Rating ScalesConnectivityDepressionNetworkSymptoms

Identifiers

PMID32047972
PMCPMC7544719

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.