ArticleJournal of animal science2020
Changes in cecal morphology, cell proliferation, antioxidant enzyme, volatile fatty acids, lipopolysaccharide, and cytokines in piglets during the postweaning period.
Article in Journal of animal science, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
19 citing papers in PubMed, 22 citations in OpenAlex.
- Effects of Pig Weaning Weight and Sex on Growth Performance, Fecal Score, and Blood Antioxidant Capacity in Early Nursery Period.Animals : an open access journal from MDPI · 2026Article
- Multi-omics analysis reveals host-microbe interactions driving divergent energy allocation strategies in Tibetan sheep under cold-season feeding regimes.Journal of animal science and biotechnology · 2025Article
- ShenQiGan Extract Repairs Intestinal Barrier in Weaning-Stressed Piglets by Modulating Inflammatory Factors, Immunoglobulins, and Short-Chain Fatty Acids.Animals : an open access journal from MDPI · 2025Article
- Dietary Synbiotic Attenuated the Intestinal Inflammation in Weaned Piglets Challenged withAnimals : an open access journal from MDPI · 2025Article
- Effects of peroxidized lipids on intestinal morphology, antioxidant capacity and gut microbiome in piglets.Animal nutrition (Zhongguo xu mu shou yi xue hui) · 2025Article
- Article
- The Mechanism of Zinc Oxide in Alleviating Diarrhea in Piglets after Weaning: A Review from the Perspective of Intestinal Barrier Function.International journal of molecular sciences · 2024Review
- Dietary nutrition, intestinal microbiota dysbiosis and post-weaning diarrhea in piglets.Animal nutrition (Zhongguo xu mu shou yi xue hui) · 2024Review
- Autolyzed yeast and sodium butyrate supplemented alone to diets promoted improvements in performance, intestinal health and nutrient transporter in weaned piglets.Scientific reports · 2024Article
- Beneficial effects of American ginseng (Frontiers in microbiology · 2024Article
- Mechanism of iron on the intestinal epithelium development in suckling piglets.Science China. Life sciences · 2023Article
- Rumen microbiota-host transcriptome interaction mediates the protective effects ofAnimal nutrition (Zhongguo xu mu shou yi xue hui) · 2023Article
- Weaning stress and intestinal health of piglets: A review.Frontiers in immunology · 2022Review
- Article
- Dietary high protein-induced diarrhea and intestinal inflammation by activation of NF-κB signaling in piglets.Animal nutrition (Zhongguo xu mu shou yi xue hui) · 2021Article
- Effects of Dietary Energy Levels on Rumen Fermentation, Gastrointestinal Tract Histology, and Bacterial Community Diversity in Fattening Male Hu Lambs.Frontiers in microbiology · 2021Article
- Effects of dietary iron level on growth performance, hematological status, and intestinal function in growing-finishing pigs.Journal of animal science · 2021Article
- Effects of dietary energy levels on rumen fermentation, microbiota, and gastrointestinal morphology in growing ewes.Food science & nutrition · 2020Article
- Flavored Vitamin-Mineral Supplementation via Water Improves the Performance of Newly Weaned Piglets.Animal science journal = Nihon chikusan GakkaihoArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Weaning stresses often induce markedly structural and functional changes in the small intestine. However, little data are available on the changes of the morphology, function, and health in the cecum of piglets post-weaning. This study was conducted to measure the effects of weaning on the cecum in piglets. Forty piglets were weaned at 21 d and samples were collected at different time points (days 0, 1, 3, 7, and 14) post-weaning. The crypt depth, crypt width, and total epithelial cell numbers increased on days 7 and 14, compared with days 0, 1, and 3 (P < 0.001). The value of Ki67/total epithelial cells was highest on day 0 compared with all other days (P < 0.05). Besides, a higher concentration of malondialdehyde was observed on day 3 (P < 0.001). The activity of CuZn-superoxide dismutase (P < 0.05) enhanced from day 0 to 1 and the activity of catalase increased from day 1 to 3 (P < 0.001). In addition, days 3, 7, and 14 had greater acetic, propanoic, and butyric acid contents than on day 1 (P < 0.001). The pH and monocarboxylate transporter 1 (MCT1) expression increased from day 0 to 1 and from day 3 to 7 and decreased between days 1 and 3 (P < 0.001). The mRNA expression of solute carrier family 9 member A3 (SLC9A3) decreased on day 1 compared to all other postweaning days (P < 0.05). The abundance of toll-like receptor 4 (TLR4) and interferon-γ (IFN-γ) mRNA expression increased (P < 0.05) during the first 24 h after weaning. The concentration of lipopolysaccharide increased from day 3 to 7, then decreased on day 14 (P < 0.05). The mRNA expression of tumor necrosis factor-α (TNF-α) enhanced from day 7 to 14 (P < 0.05). The abundance of phosphorylated mammalian target of rapamycin protein was lower on day 14 than day 0 (P < 0.05). Taken together, these results show that weaning in piglets influences intestinal morphology, function, and health in the cecum.
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